The effect of gamma-type endorphins on alpha-MSH release in the rat

Neuroleptic drugs increase the level of alpha-melanotropin (alpha-MSH) in the blood of the rat. We have investigated whether neuroleptic-like peptides, the gamma-type endorphins, also affect alpha-MSH release. A structure-activity study revealed that (des-enkephalin)-gamma-endorphin (DE gamma E, bet...

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Veröffentlicht in:	Life sciences (1973) 1985-07, Vol.37 (3), p.263-271
Hauptverfasser:	de Rotte, A A, van Wimersma Greidanus, T B, van de Buuse, M, Andringa-Bakker, E A, de Wied, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - pharmacology Apomorphine - pharmacology beta-Endorphin Dose-Response Relationship, Drug endorphins Endorphins - administration & dosage Endorphins - pharmacology gamma-Endorphin Haloperidol - pharmacology Injections, Intraventricular Male melanocyte-stimulating hormone Melanocyte-Stimulating Hormones - blood Melanocyte-Stimulating Hormones - metabolism Naloxone - pharmacology Pituitary Gland, Anterior - drug effects Pituitary Gland, Anterior - metabolism Rats Rats, Inbred Strains
Online-Zugang:	Volltext
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