Midwall left ventricular performance in salt-loaded Dahl rats: effect of AT1 angiotensin II inhibition

OBJECTIVEThe relationship between left ventricular midwall shortening and circumferential end-systolic stress was studied in Dahl salt-sensitive (Dahl S) and salt-resistant (Dahl R) rats after 6–8 weeks of an 8% Na diet with or without losartan, an AT1 angiotensin II receptor antagonist. MATERIALS A...

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Veröffentlicht in:	Journal of hypertension 1995-12, Vol.13 (12), p.1808-1812
Hauptverfasser:	Simone, Giovanni De, Devereux, Richard B, Camargo, Maria J.F, Wallerson, Donald C, Sealey, Jean E, Laragh, John H
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Receptor Antagonists Animals Antihypertensive agents Antihypertensive Agents - pharmacology Biological and medical sciences Biphenyl Compounds - pharmacology Cardiovascular system Echocardiography Imidazoles - pharmacology Losartan Male Medical sciences Myocardial Contraction - drug effects Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Rats, Wistar Tetrazoles - pharmacology Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - drug therapy Ventricular Dysfunction, Left - physiopathology
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