Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study
We investigated the relation of psychosocial risk factors to mortality in a prospective study of 1353 inhabitants of Crvenka, 619 of whom died between 1966 and 1976. All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppressi...
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Veröffentlicht in: | Journal of psychosomatic research 1985, Vol.29 (2), p.167-176 |
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description | We investigated the relation of psychosocial risk factors to mortality in a prospective study of 1353 inhabitants of Crvenka, 619 of whom died between 1966 and 1976. All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppression of aggression. Compared with lower R/A, high R/A was also associated with a relative risk of mortality of 29 for other cancer, 4.3 for ischaemic heart disease and 6.5 for stroke. Standardising for R/A reduced the smoking/lung cancer association, virtually eliminated the smoking/other cancer and smoking/heart disease relationships and reduced the association of heart disease with blood cholesterol, blood sugar and hypertension. Long lasting hopelesness was also independently associated with cancer as was anger with heart disease, though not so strongly as for R/A. Psychosocial variables are important predictors of mortality and decisively modify the effect of physical risk factors such as smoking. |
doi_str_mv | 10.1016/0022-3999(85)90038-8 |
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All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppression of aggression. Compared with lower R/A, high R/A was also associated with a relative risk of mortality of 29 for other cancer, 4.3 for ischaemic heart disease and 6.5 for stroke. Standardising for R/A reduced the smoking/lung cancer association, virtually eliminated the smoking/other cancer and smoking/heart disease relationships and reduced the association of heart disease with blood cholesterol, blood sugar and hypertension. Long lasting hopelesness was also independently associated with cancer as was anger with heart disease, though not so strongly as for R/A. Psychosocial variables are important predictors of mortality and decisively modify the effect of physical risk factors such as smoking.</description><identifier>ISSN: 0022-3999</identifier><identifier>EISSN: 1879-1360</identifier><identifier>DOI: 10.1016/0022-3999(85)90038-8</identifier><identifier>PMID: 4009517</identifier><identifier>CODEN: JPCRAT</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>Biological and medical sciences ; Cerebral Infarction - mortality ; Cerebral Infarction - psychology ; Coronary Disease - mortality ; Coronary Disease - psychology ; Emotions ; Female ; Follow-Up Studies ; General aspects ; Humans ; Lung Neoplasms - psychology ; Male ; Medical sciences ; Middle Aged ; Neoplasms - mortality ; Neoplasms - psychology ; Personality ; Prospective Studies ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychophysiologic Disorders - psychology ; Risk ; Smoking ; Yugoslavia</subject><ispartof>Journal of psychosomatic research, 1985, Vol.29 (2), p.167-176</ispartof><rights>1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-ea1bea11e88ab8c1a8c077a4bbca1b635882a864f16f53ca03ad7a4ca9652eb03</citedby><cites>FETCH-LOGICAL-c421t-ea1bea11e88ab8c1a8c077a4bbca1b635882a864f16f53ca03ad7a4ca9652eb03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0022-3999(85)90038-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8719094$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4009517$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grossarth-Maticek, Ronald</creatorcontrib><creatorcontrib>Bastiaans, Jan</creatorcontrib><creatorcontrib>Kanazir, Dusan T.</creatorcontrib><title>Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study</title><title>Journal of psychosomatic research</title><addtitle>J Psychosom Res</addtitle><description>We investigated the relation of psychosocial risk factors to mortality in a prospective study of 1353 inhabitants of Crvenka, 619 of whom died between 1966 and 1976. All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppression of aggression. Compared with lower R/A, high R/A was also associated with a relative risk of mortality of 29 for other cancer, 4.3 for ischaemic heart disease and 6.5 for stroke. Standardising for R/A reduced the smoking/lung cancer association, virtually eliminated the smoking/other cancer and smoking/heart disease relationships and reduced the association of heart disease with blood cholesterol, blood sugar and hypertension. Long lasting hopelesness was also independently associated with cancer as was anger with heart disease, though not so strongly as for R/A. Psychosocial variables are important predictors of mortality and decisively modify the effect of physical risk factors such as smoking.</description><subject>Biological and medical sciences</subject><subject>Cerebral Infarction - mortality</subject><subject>Cerebral Infarction - psychology</subject><subject>Coronary Disease - mortality</subject><subject>Coronary Disease - psychology</subject><subject>Emotions</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Humans</subject><subject>Lung Neoplasms - psychology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasms - mortality</subject><subject>Neoplasms - psychology</subject><subject>Personality</subject><subject>Prospective Studies</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychophysiologic Disorders - psychology</subject><subject>Risk</subject><subject>Smoking</subject><subject>Yugoslavia</subject><issn>0022-3999</issn><issn>1879-1360</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM2KFDEUhYMoYzv6BgpZiChYmtRPKnEhyOAfDOhiXLgKt27dmo5WddrcqoZ-AZ_b9HTTSxchkPPlcPiEeKrVG620eatUWRaVc-6lbV45pSpb2HtipW3rCl0ZdV-szshD8Yj5l1LKuLK5EBe1Uq7R7Ur8_c57XEeOGGCUA-AcE0tgyXOKm1u5TdSH42Mc5BTTDGOY93JIcZIIG6T0WgbGNdAUUK4J0iz7wARMEjb9Xc9veidv1iR_LreRR9jl1shbwjnsKANLv38sHgwwMj053Zfix6ePN1dfiutvn79efbgusC71XBDoLh9N1kJnUYNF1bZQdx3mxFSNtSVYUw_aDE2FoCroc4zgTFNSp6pL8eLYmxf8WYhnP-XxNI6wobiwb41uTdNWGayPIOapnGjw2xQmSHuvlT_o9we3_uDW28bf6fc2f3t26l-6ifrzp5PvnD8_5cAI45CywcBnzLbaKVdn7P0Ro-xiFyh5xkBZdh9S1ub7GP6_4x9ei6SH</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Grossarth-Maticek, Ronald</creator><creator>Bastiaans, Jan</creator><creator>Kanazir, Dusan T.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1985</creationdate><title>Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study</title><author>Grossarth-Maticek, Ronald ; Bastiaans, Jan ; Kanazir, Dusan T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-ea1bea11e88ab8c1a8c077a4bbca1b635882a864f16f53ca03ad7a4ca9652eb03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Biological and medical sciences</topic><topic>Cerebral Infarction - mortality</topic><topic>Cerebral Infarction - psychology</topic><topic>Coronary Disease - mortality</topic><topic>Coronary Disease - psychology</topic><topic>Emotions</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Humans</topic><topic>Lung Neoplasms - psychology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasms - mortality</topic><topic>Neoplasms - psychology</topic><topic>Personality</topic><topic>Prospective Studies</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychophysiologic Disorders - psychology</topic><topic>Risk</topic><topic>Smoking</topic><topic>Yugoslavia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grossarth-Maticek, Ronald</creatorcontrib><creatorcontrib>Bastiaans, Jan</creatorcontrib><creatorcontrib>Kanazir, Dusan T.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychosomatic research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grossarth-Maticek, Ronald</au><au>Bastiaans, Jan</au><au>Kanazir, Dusan T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study</atitle><jtitle>Journal of psychosomatic research</jtitle><addtitle>J Psychosom Res</addtitle><date>1985</date><risdate>1985</risdate><volume>29</volume><issue>2</issue><spage>167</spage><epage>176</epage><pages>167-176</pages><issn>0022-3999</issn><eissn>1879-1360</eissn><coden>JPCRAT</coden><abstract>We investigated the relation of psychosocial risk factors to mortality in a prospective study of 1353 inhabitants of Crvenka, 619 of whom died between 1966 and 1976. All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppression of aggression. Compared with lower R/A, high R/A was also associated with a relative risk of mortality of 29 for other cancer, 4.3 for ischaemic heart disease and 6.5 for stroke. Standardising for R/A reduced the smoking/lung cancer association, virtually eliminated the smoking/other cancer and smoking/heart disease relationships and reduced the association of heart disease with blood cholesterol, blood sugar and hypertension. Long lasting hopelesness was also independently associated with cancer as was anger with heart disease, though not so strongly as for R/A. Psychosocial variables are important predictors of mortality and decisively modify the effect of physical risk factors such as smoking.</abstract><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>4009517</pmid><doi>10.1016/0022-3999(85)90038-8</doi><tpages>10</tpages></addata></record> |
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subjects | Biological and medical sciences Cerebral Infarction - mortality Cerebral Infarction - psychology Coronary Disease - mortality Coronary Disease - psychology Emotions Female Follow-Up Studies General aspects Humans Lung Neoplasms - psychology Male Medical sciences Middle Aged Neoplasms - mortality Neoplasms - psychology Personality Prospective Studies Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychophysiologic Disorders - psychology Risk Smoking Yugoslavia |
title | Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study |
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