Toluene diisocyanate-stimulated release of arachidonic acid metabolites in the organ bath from guinea-pig airways

This study was designed to evaluate whether metabolites of arachidonic acid play a role in the contractile response to toluene diisocyanate in isolated guinea pig airways. In control experiments we collected the supernatant from an organ bath over a time period of 2 h, after the addition to toluene...

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Veröffentlicht in:	European journal of pharmacology 1993-10, Vol.248 (3), p.277-280
Hauptverfasser:	Mapp, Cristina Elisabetta, Boniotti, Anna, Masiero, Mauro, Plebani, Mario, Burlina, Angelo, Papi, Alberto, Maestrelli, Piero, Saetta, Marina, Ciaccia, Adalberto, Fabbri, Leonardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acids - metabolism Bronchi - drug effects Bronchi - metabolism Guinea Pigs In Vitro Techniques Indomethacin - pharmacology Male Prostaglandins - metabolism Prostanoids Sensory nerves Toluene 2,4-Diisocyanate - pharmacology Toluene diisocyanate
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