A NOVEL QUINONE ANTIBIOTIC FROM Malbranchea cinnamomea TAIM 13T54

A novel quinone antibiotic named malbranicin was isolated from the culture filtrate and mycelium of Malbranchea cinnamomea TAIM 13T54, a thermophilic fungus. The antibiotic was elucidated to be 6-(1-acetylethyl)-2-methoxy-2, 5-cyclohexadiene-1, 4-dione by spectral analysis. Malbranicin exhibited ant...

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Veröffentlicht in:	Journal of antibiotics 1993/12/25, Vol.46(12), pp.1819-1826
Hauptverfasser:	CHIUNG, YIN-MEI, FUJITA, TOMOYUKI, NAKAGAWA, MASAHIRA, NOZAKI, HIROSHI, CHEN, GUEH-YUH, CHEN, ZUEI-CHING, NAKAYAMA, MITSURU
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - biosynthesis Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Applied microbiology Benzoquinones Biological and medical sciences Chemical Phenomena Chemistry, Physical Fermentation Fundamental and applied biological sciences. Psychology Fungi - chemistry Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans KB Cells Leukemia P388 - drug therapy Magnetic Resonance Spectroscopy Mice Microbial Sensitivity Tests Microbiology Molecular Structure Quinones - chemistry Quinones - isolation & purification Quinones - metabolism Quinones - pharmacology
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