Nonspecific defense mechanisms of the eye
It has long been recognized that important nonspecific defense mechanisms protect the eye from the multitudinous microbial insults to which it is subjected in the course of everyday life. It is also well known that the tears, with their ability to flush airborne and other microbes into the nose, are...
Gespeichert in:
| Veröffentlicht in: | International ophthalmology clinics 1985, Vol.25 (2), p.1-11 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 11 |
|---|---|
| container_issue | 2 |
| container_start_page | 1 |
| container_title | International ophthalmology clinics |
| container_volume | 25 |
| creator | Thygeson, P |
| description | It has long been recognized that important nonspecific defense mechanisms protect the eye from the multitudinous microbial insults to which it is subjected in the course of everyday life. It is also well known that the tears, with their ability to flush airborne and other microbes into the nose, are largely responsible for this protection. Ophthalmologists have long known that any interference with lacrimal drainage, or a lack of tears for any reason, predispose the external eye, particularly the conjunctiva and cornea, to infection. In all, there are three defense mechanisms for the eye: (1) the protection afforded by the skin and mucous membranes; (2) the acute inflammatory reaction; and (3) the development of specific humoral or cellular immunity. The first two are nonspecific and the principal subjects of this review. |
| doi_str_mv | 10.1097/00004397-198502520-00003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76170304</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76170304</sourcerecordid><originalsourceid>FETCH-LOGICAL-c286t-e47b5f420e8a17c35c4a5830532b69f34292b1d977b17f267e695225cd299c213</originalsourceid><addsrcrecordid>eNqFkEFPwzAMhXMAjTH4CUg9IXEoOE5SN0c0wUCa4ALnqE0drWhtR9Md9u_p2NgVXyw_vWfLnxCJhHsJlh5gLK0spdLmBtAgpHtJnYkpwDjkMqMLcRnjF4AkhXYiJqjBgoapuHvr2rhhX4faJxUHbiMnDftV0daxiUkXkmHFCe_4SpyHYh35-thn4vP56WP-ki7fF6_zx2XqMc-GlDWVJmgEzgtJXhmvC5MrMArLzAal0WIpK0tUSgqYEWfWIBpfobUepZqJ28PeTd99bzkOrqmj5_W6aLnbRkeZJFDjx_8ZpVYGyeBozA9G33cx9hzcpq-bot85CW6P0P0hdCeEv5IaozfHG9uy4eoUPPJTP28caxg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14352752</pqid></control><display><type>article</type><title>Nonspecific defense mechanisms of the eye</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Thygeson, P</creator><creatorcontrib>Thygeson, P</creatorcontrib><description>It has long been recognized that important nonspecific defense mechanisms protect the eye from the multitudinous microbial insults to which it is subjected in the course of everyday life. It is also well known that the tears, with their ability to flush airborne and other microbes into the nose, are largely responsible for this protection. Ophthalmologists have long known that any interference with lacrimal drainage, or a lack of tears for any reason, predispose the external eye, particularly the conjunctiva and cornea, to infection. In all, there are three defense mechanisms for the eye: (1) the protection afforded by the skin and mucous membranes; (2) the acute inflammatory reaction; and (3) the development of specific humoral or cellular immunity. The first two are nonspecific and the principal subjects of this review.</description><identifier>ISSN: 0020-8167</identifier><identifier>DOI: 10.1097/00004397-198502520-00003</identifier><identifier>PMID: 2409040</identifier><language>eng</language><publisher>United States</publisher><subject>Acute Disease ; Biomechanical Phenomena ; Climate ; Dermatitis, Atopic - physiopathology ; Epidemiology ; Epithelial Cells ; Epithelium - physiology ; Fever - physiopathology ; Genetics ; Humans ; Immunity, Innate ; Inflammation - physiopathology ; Interferons - physiology ; Mucous Membrane - physiology ; Ocular Physiological Phenomena ; Sex Factors ; Skin Physiological Phenomena ; Species Specificity ; Stress, Physiological - physiopathology</subject><ispartof>International ophthalmology clinics, 1985, Vol.25 (2), p.1-11</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,4010,27904,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2409040$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thygeson, P</creatorcontrib><title>Nonspecific defense mechanisms of the eye</title><title>International ophthalmology clinics</title><addtitle>Int Ophthalmol Clin</addtitle><description>It has long been recognized that important nonspecific defense mechanisms protect the eye from the multitudinous microbial insults to which it is subjected in the course of everyday life. It is also well known that the tears, with their ability to flush airborne and other microbes into the nose, are largely responsible for this protection. Ophthalmologists have long known that any interference with lacrimal drainage, or a lack of tears for any reason, predispose the external eye, particularly the conjunctiva and cornea, to infection. In all, there are three defense mechanisms for the eye: (1) the protection afforded by the skin and mucous membranes; (2) the acute inflammatory reaction; and (3) the development of specific humoral or cellular immunity. The first two are nonspecific and the principal subjects of this review.</description><subject>Acute Disease</subject><subject>Biomechanical Phenomena</subject><subject>Climate</subject><subject>Dermatitis, Atopic - physiopathology</subject><subject>Epidemiology</subject><subject>Epithelial Cells</subject><subject>Epithelium - physiology</subject><subject>Fever - physiopathology</subject><subject>Genetics</subject><subject>Humans</subject><subject>Immunity, Innate</subject><subject>Inflammation - physiopathology</subject><subject>Interferons - physiology</subject><subject>Mucous Membrane - physiology</subject><subject>Ocular Physiological Phenomena</subject><subject>Sex Factors</subject><subject>Skin Physiological Phenomena</subject><subject>Species Specificity</subject><subject>Stress, Physiological - physiopathology</subject><issn>0020-8167</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFPwzAMhXMAjTH4CUg9IXEoOE5SN0c0wUCa4ALnqE0drWhtR9Md9u_p2NgVXyw_vWfLnxCJhHsJlh5gLK0spdLmBtAgpHtJnYkpwDjkMqMLcRnjF4AkhXYiJqjBgoapuHvr2rhhX4faJxUHbiMnDftV0daxiUkXkmHFCe_4SpyHYh35-thn4vP56WP-ki7fF6_zx2XqMc-GlDWVJmgEzgtJXhmvC5MrMArLzAal0WIpK0tUSgqYEWfWIBpfobUepZqJ28PeTd99bzkOrqmj5_W6aLnbRkeZJFDjx_8ZpVYGyeBozA9G33cx9hzcpq-bot85CW6P0P0hdCeEv5IaozfHG9uy4eoUPPJTP28caxg</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Thygeson, P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>1985</creationdate><title>Nonspecific defense mechanisms of the eye</title><author>Thygeson, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c286t-e47b5f420e8a17c35c4a5830532b69f34292b1d977b17f267e695225cd299c213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Acute Disease</topic><topic>Biomechanical Phenomena</topic><topic>Climate</topic><topic>Dermatitis, Atopic - physiopathology</topic><topic>Epidemiology</topic><topic>Epithelial Cells</topic><topic>Epithelium - physiology</topic><topic>Fever - physiopathology</topic><topic>Genetics</topic><topic>Humans</topic><topic>Immunity, Innate</topic><topic>Inflammation - physiopathology</topic><topic>Interferons - physiology</topic><topic>Mucous Membrane - physiology</topic><topic>Ocular Physiological Phenomena</topic><topic>Sex Factors</topic><topic>Skin Physiological Phenomena</topic><topic>Species Specificity</topic><topic>Stress, Physiological - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thygeson, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International ophthalmology clinics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thygeson, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonspecific defense mechanisms of the eye</atitle><jtitle>International ophthalmology clinics</jtitle><addtitle>Int Ophthalmol Clin</addtitle><date>1985</date><risdate>1985</risdate><volume>25</volume><issue>2</issue><spage>1</spage><epage>11</epage><pages>1-11</pages><issn>0020-8167</issn><abstract>It has long been recognized that important nonspecific defense mechanisms protect the eye from the multitudinous microbial insults to which it is subjected in the course of everyday life. It is also well known that the tears, with their ability to flush airborne and other microbes into the nose, are largely responsible for this protection. Ophthalmologists have long known that any interference with lacrimal drainage, or a lack of tears for any reason, predispose the external eye, particularly the conjunctiva and cornea, to infection. In all, there are three defense mechanisms for the eye: (1) the protection afforded by the skin and mucous membranes; (2) the acute inflammatory reaction; and (3) the development of specific humoral or cellular immunity. The first two are nonspecific and the principal subjects of this review.</abstract><cop>United States</cop><pmid>2409040</pmid><doi>10.1097/00004397-198502520-00003</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0020-8167 |
| ispartof | International ophthalmology clinics, 1985, Vol.25 (2), p.1-11 |
| issn | 0020-8167 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76170304 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Acute Disease Biomechanical Phenomena Climate Dermatitis, Atopic - physiopathology Epidemiology Epithelial Cells Epithelium - physiology Fever - physiopathology Genetics Humans Immunity, Innate Inflammation - physiopathology Interferons - physiology Mucous Membrane - physiology Ocular Physiological Phenomena Sex Factors Skin Physiological Phenomena Species Specificity Stress, Physiological - physiopathology |
| title | Nonspecific defense mechanisms of the eye |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T20%3A19%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nonspecific%20defense%20mechanisms%20of%20the%20eye&rft.jtitle=International%20ophthalmology%20clinics&rft.au=Thygeson,%20P&rft.date=1985&rft.volume=25&rft.issue=2&rft.spage=1&rft.epage=11&rft.pages=1-11&rft.issn=0020-8167&rft_id=info:doi/10.1097/00004397-198502520-00003&rft_dat=%3Cproquest_cross%3E76170304%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14352752&rft_id=info:pmid/2409040&rfr_iscdi=true |