Effect of ramipril on α-adrenoceptor-mediated oscillatory contractions in tail artery of hypertensive rats

Recent studies indicate that norepinephrine-induced contractile oscillations in the tail artery from stroke-prone spontaneously hypertensive rats (SHRSP) may be a vascular phenomenon independent of blood pressure level. The objectives of this study were: (1) to characterize pharmacologically the α-a...

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Veröffentlicht in:	European journal of pharmacology 1993-10, Vol.242 (3), p.245-253
Hauptverfasser:	Watts, Stephanie W., Traub, Oren, Lamb, Fred S., Myers, J.Hurley, Webb, R.Clinton
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenoceptors Animals Arterial hypertension. Arterial hypotension Arteries - drug effects Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Cardiology. Vascular system Cerebrovascular Disorders - genetics Disease Susceptibility Experimental diseases Genetic hypertension Hypertension - genetics Hypertension - physiopathology Medical sciences Muscle, Smooth, Vascular - drug effects Norepinephrine - antagonists & inhibitors Norepinephrine - pharmacology Oscillation Periodicity Ramipril Ramipril - pharmacology Rats Rats, Inbred SHR Rats, Inbred WKY Receptors, Adrenergic, alpha - drug effects Tail - blood supply Vasoconstriction - drug effects
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