Glycyl- l-glutamine antagonizes α-MSH-elicited thermogenesis

The objective of this study was to determine whether glycyl- l-glutamine [β-endorphin(30–31)] modulates the thermoregulatory actions of α-MSH. Microinjection of α-MSH (0.06 nmol) into PGE 2-responsive thermogenic sites in the medial preoptic area of rats generated a hyperthermic response, inducing a...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1993-09, Vol.14 (5), p.971-975
Hauptverfasser:	Resch, Garth E., Millington, William R.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-MSH - administration & dosage alpha-MSH - antagonists & inhibitors Animals Biological and medical sciences Body Temperature Regulation - drug effects Dinoprostone - pharmacology Dipeptide Dipeptides - administration & dosage Fundamental and applied biological sciences. Psychology Glycyl- l-glutamine Male Neural Inhibition Preoptic area Preoptic Area - drug effects Proopiomelanocortin Rats Rats, Sprague-Dawley Thermoregulation Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects Vertebrates: anatomy and physiology, studies on body, several organs or systems α-MSH β-Endorphin
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