Viability of tumor cells in the irrigation fluid of the cavitron ultrasonic surgical aspirator (CUSA) after tumor fragmentation

The Cavitron Ultrasonic Surgical Aspirator (CUSA) (Cooper Medical, Stamford, CT) is a relatively new surgical modality. The risk of tumor seeding during tumor surgery has not been studied until now. Hanks balanced salt solution, normal saline, distilled water, and Dakin's solution were used as...

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Veröffentlicht in:Cancer 1985-07, Vol.56 (2), p.368-370
Hauptverfasser: Oosterhuis, Jan W., Lung, Paul F. Liqui, Verschueren, René C. J., Oldhoff, Jan
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container_end_page 370
container_issue 2
container_start_page 368
container_title Cancer
container_volume 56
creator Oosterhuis, Jan W.
Lung, Paul F. Liqui
Verschueren, René C. J.
Oldhoff, Jan
description The Cavitron Ultrasonic Surgical Aspirator (CUSA) (Cooper Medical, Stamford, CT) is a relatively new surgical modality. The risk of tumor seeding during tumor surgery has not been studied until now. Hanks balanced salt solution, normal saline, distilled water, and Dakin's solution were used as irrigation fluids during CUSA fragmentation of Lewis lung carcinoma in C57BI/10 female mice, using the machine at 40% of its maximal output. All four irrigation fluids contained viable tumor cells—growing in vitro as well as in vivo—after tumor aspiration. Normal saline was also used when the machine was operating at its maximal output. Under these conditions, the irrigation fluid contained viable tumor cells as well.
doi_str_mv 10.1002/1097-0142(19850715)56:2<368::AID-CNCR2820560227>3.0.CO;2-4
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subjects Animals
Biological and medical sciences
Female
Hindlimb
Medical sciences
Mice
Mice, Inbred C57BL
Neoplasm Seeding
Neoplasms - pathology
Neoplasms - therapy
Solutions
Treatment. General aspects
Tumors
Ultrasonic Therapy - adverse effects
Ultrasonic Therapy - instrumentation
title Viability of tumor cells in the irrigation fluid of the cavitron ultrasonic surgical aspirator (CUSA) after tumor fragmentation
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