Acetylation of lens crystallins: A possible mechanism by which aspirin could prevent cataract formation

The calf eye lens homogenate incubated with [1- 14C-acetyl] aspirin and separated into HMW, α, β H, β L and γ-crystallins by means of Sepharose 6B and Bio-Gel P2 columns showed radioactivity in all the crystallins. In contrast, no radioactivity was found in the crystallins when the lens homogenate w...

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