Transfer and expression of the human interleukin-4 gene in carcinoma and stromal cell lines derived from lung cancer patients

Introduction of the interleukin-4 (IL-4) gene into cells derived from human tumor tissue provides a means for generating a specific tumor vaccine. Such a vaccine could be produced by either transducing tumor-derived stromal cells with the IL-4 vector and coinjecting tumor cells, or by transducing th...

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