Lactogenic hormones and extracellular matrix regulate expression of IGF-1 linked to MMTV-LTR in mammary epithelial cells

The cell line MD-IGF-1, containing an ovine IGF-1 cDNA driven by the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promoter, was used to study expression of IGF-1 linked to the MMTV-LTR in bovine mammary epithelial cells in response to various hormonal and substratum stimuli. Acute sensi...

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Veröffentlicht in:	Molecular and cellular endocrinology 1993-10, Vol.96 (1), p.147-157
Hauptverfasser:	Romagnoloa, Donate, Michael Akers, R., Wong, Eric A., Boyle, Pat L., McFadden, Thomas B., Byatt, John C., Turner, Jeffrey D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Breast - cytology Breast - metabolism Cattle Cell Line Epithelial Cells Epithelium - metabolism Extracellular matrix Extracellular Matrix - physiology Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Growth Growth Substances - physiology Hormones - physiology IGF-1 Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Lactogenic hormone Mammary epithelial cell (bovine) Mammary Tumor Virus, Mouse - genetics MMTV-LTR Molecular and cellular biology Molecular genetics Mouse mammary tumor virus-long terminal repeat Promoter Regions, Genetic Repetitive Sequences, Nucleic Acid Sheep
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