Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome
The ribosomal DNA locus of Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified cis-acting ele...
Gespeichert in:
| Veröffentlicht in: | Current opinion in genetics & development 1993-10, Vol.3 (5), p.730-735 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 735 |
|---|---|
| container_issue | 5 |
| container_start_page | 730 |
| container_title | Current opinion in genetics & development |
| container_volume | 3 |
| creator | Kapler, Geoffrey M. |
| description | The ribosomal DNA locus of
Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified
cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance. |
| doi_str_mv | 10.1016/S0959-437X(05)80091-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76135726</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0959437X05800917</els_id><sourcerecordid>16698588</sourcerecordid><originalsourceid>FETCH-LOGICAL-c391t-dcc088b76b2574a0ec13b1e52ccc89770b58878584f0d2d076da44594e40ecb93</originalsourceid><addsrcrecordid>eNqFkEtLxDAUhYMoOj5-gtCV6KJ60zZNshIZnzDoQgXBRUiTO06kbcakMzD_3ugMbl1lcb5zT_gIOaZwToHWF88gmcyrkr-dAjsTAJLmfIuMqOAyh1LANhn9IXtkP8ZPACgorXfJrih4JRgbkfdrXGLr5x32g27bVRbwY9HqAW02D95gjK7_yHRvUzBvndGD833mp9kww-wFh6Bnq9TVWbh-vMo61zszC77z0Xd4SHamuo14tHkPyOvtzcv4Pp883T2Mrya5KSUdcmsMCNHwuikYrzSgoWVDkRXGGCE5h4YJwQUT1RRsYYHXVlcVkxVWiW1keUBO1nfTj78WGAfVuWiwbXWPfhEVr2nJeFH_C9K6lmlHJJCtQRN8jAGnah5cp8NKUVA_9tWvffWjVgFTv_YVT73jzcCi6dD-tTa6U365zjHpWDoMKhqHvUHrAppBWe_-WfgG_Y-V-Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>16698588</pqid></control><display><type>article</type><title>Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Kapler, Geoffrey M.</creator><creatorcontrib>Kapler, Geoffrey M.</creatorcontrib><description>The ribosomal DNA locus of
Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified
cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.</description><identifier>ISSN: 0959-437X</identifier><identifier>EISSN: 1879-0380</identifier><identifier>DOI: 10.1016/S0959-437X(05)80091-7</identifier><identifier>PMID: 8274855</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Chromosomes ; DNA Replication ; DNA, Protozoan - biosynthesis ; DNA, Ribosomal - biosynthesis ; Tetrahymena thermophila ; Tetrahymena thermophila - genetics ; Tetrahymena thermophila - growth & development</subject><ispartof>Current opinion in genetics & development, 1993-10, Vol.3 (5), p.730-735</ispartof><rights>1993 Current Biology Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-dcc088b76b2574a0ec13b1e52ccc89770b58878584f0d2d076da44594e40ecb93</citedby><cites>FETCH-LOGICAL-c391t-dcc088b76b2574a0ec13b1e52ccc89770b58878584f0d2d076da44594e40ecb93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0959-437X(05)80091-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8274855$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kapler, Geoffrey M.</creatorcontrib><title>Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome</title><title>Current opinion in genetics & development</title><addtitle>Curr Opin Genet Dev</addtitle><description>The ribosomal DNA locus of
Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified
cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.</description><subject>Animals</subject><subject>Chromosomes</subject><subject>DNA Replication</subject><subject>DNA, Protozoan - biosynthesis</subject><subject>DNA, Ribosomal - biosynthesis</subject><subject>Tetrahymena thermophila</subject><subject>Tetrahymena thermophila - genetics</subject><subject>Tetrahymena thermophila - growth & development</subject><issn>0959-437X</issn><issn>1879-0380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAUhYMoOj5-gtCV6KJ60zZNshIZnzDoQgXBRUiTO06kbcakMzD_3ugMbl1lcb5zT_gIOaZwToHWF88gmcyrkr-dAjsTAJLmfIuMqOAyh1LANhn9IXtkP8ZPACgorXfJrih4JRgbkfdrXGLr5x32g27bVRbwY9HqAW02D95gjK7_yHRvUzBvndGD833mp9kww-wFh6Bnq9TVWbh-vMo61zszC77z0Xd4SHamuo14tHkPyOvtzcv4Pp883T2Mrya5KSUdcmsMCNHwuikYrzSgoWVDkRXGGCE5h4YJwQUT1RRsYYHXVlcVkxVWiW1keUBO1nfTj78WGAfVuWiwbXWPfhEVr2nJeFH_C9K6lmlHJJCtQRN8jAGnah5cp8NKUVA_9tWvffWjVgFTv_YVT73jzcCi6dD-tTa6U365zjHpWDoMKhqHvUHrAppBWe_-WfgG_Y-V-Q</recordid><startdate>19931001</startdate><enddate>19931001</enddate><creator>Kapler, Geoffrey M.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>19931001</creationdate><title>Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome</title><author>Kapler, Geoffrey M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-dcc088b76b2574a0ec13b1e52ccc89770b58878584f0d2d076da44594e40ecb93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Animals</topic><topic>Chromosomes</topic><topic>DNA Replication</topic><topic>DNA, Protozoan - biosynthesis</topic><topic>DNA, Ribosomal - biosynthesis</topic><topic>Tetrahymena thermophila</topic><topic>Tetrahymena thermophila - genetics</topic><topic>Tetrahymena thermophila - growth & development</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kapler, Geoffrey M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in genetics & development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kapler, Geoffrey M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome</atitle><jtitle>Current opinion in genetics & development</jtitle><addtitle>Curr Opin Genet Dev</addtitle><date>1993-10-01</date><risdate>1993</risdate><volume>3</volume><issue>5</issue><spage>730</spage><epage>735</epage><pages>730-735</pages><issn>0959-437X</issn><eissn>1879-0380</eissn><abstract>The ribosomal DNA locus of
Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified
cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>8274855</pmid><doi>10.1016/S0959-437X(05)80091-7</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0959-437X |
| ispartof | Current opinion in genetics & development, 1993-10, Vol.3 (5), p.730-735 |
| issn | 0959-437X 1879-0380 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76135726 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Chromosomes DNA Replication DNA, Protozoan - biosynthesis DNA, Ribosomal - biosynthesis Tetrahymena thermophila Tetrahymena thermophila - genetics Tetrahymena thermophila - growth & development |
| title | Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T17%3A41%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Developmentally%20regulated%20processing%20and%20replication%20of%20the%20Tetrahymena%20rDNA%20minichromosome&rft.jtitle=Current%20opinion%20in%20genetics%20&%20development&rft.au=Kapler,%20Geoffrey%20M.&rft.date=1993-10-01&rft.volume=3&rft.issue=5&rft.spage=730&rft.epage=735&rft.pages=730-735&rft.issn=0959-437X&rft.eissn=1879-0380&rft_id=info:doi/10.1016/S0959-437X(05)80091-7&rft_dat=%3Cproquest_cross%3E16698588%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=16698588&rft_id=info:pmid/8274855&rft_els_id=S0959437X05800917&rfr_iscdi=true |