Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome

The ribosomal DNA locus of Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified cis-acting ele...

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Veröffentlicht in:	Current opinion in genetics & development 1993-10, Vol.3 (5), p.730-735
1. Verfasser:	Kapler, Geoffrey M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosomes DNA Replication DNA, Protozoan - biosynthesis DNA, Ribosomal - biosynthesis Tetrahymena thermophila Tetrahymena thermophila - genetics Tetrahymena thermophila - growth & development
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The ribosomal DNA locus of Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.
ISSN:	0959-437X 1879-0380
DOI:	10.1016/S0959-437X(05)80091-7