Etoposide-resistant human colon and lung adenocarcinoma cell lines exhibit sensitivity to homoharringtonine

Human colon (HCT116/VP48) and lung (A549B/VP29) adenocarcinoma cell lines selected for resistance to etoposide exhibited modified patterns of multi-drug resistance (MDR) that included a differential sensitivity to other DNA topoisomerase II inhibitors and to the plant alkaloids homoharringtonine, vi...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 1993, Vol.33 (2), p.149-153
Hauptverfasser:	WILKOFF, L. J, DULMADGE, E. A, GEETHA VASANTHAKUMAR, DONAHUE, J. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Antineoplastic agents Antineoplastic Agents - pharmacology Antineoplastic Agents, Phytogenic - pharmacology Biological and medical sciences Colonic Neoplasms - drug therapy Drug Resistance Etoposide - pharmacology General aspects Harringtonines - pharmacology Homoharringtonine Humans Lung Neoplasms - drug therapy Medical sciences Pharmacology. Drug treatments Tumor Cells, Cultured
Online-Zugang:	Volltext
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