A role for the spleen in the appearance of IgM in the bile of rats injected intravenously with horse erythrocytes

The i.v. injection of the particulate antigens horse red blood cells (HRBC) and Salmonella enteritidis into rats results in the appearance of high levels of IgM agglutinating antibody in the serum and bile. This is in contrast to the appearance of specific IgA antibodies in bile after the injection...

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Veröffentlicht in:	The Journal of immunology (1950) 1985-07, Vol.135 (1), p.152-157
Hauptverfasser:	Jackson, GD, Walker, PG, Schiff, JM, Barrington, PJ, Fisher, MM, Underdown, BJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Bile - immunology Bile - metabolism Biological Transport, Active Blood Group Antigens - immunology Exact sciences and technology Female Horses - immunology Immunoglobulin M - biosynthesis Immunoglobulin M - metabolism Injections, Intravenous Male Other techniques and industries Rats Rats, Inbred Strains Secretory Component - analysis Spleen - physiology Splenectomy Time Factors
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