A morphological biosensor for mammalian cells

An electrical biosensor is described that can continuously track morphological changes of adherent cells providing quantitative data from both sparse and confluent cultures. The method is capable of detecting vertical motion of cells of the order of 1 nm, much below the resolution of an optical micr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1993-12, Vol.366 (6455), p.591-592
Hauptverfasser:	Giaever, Ivar, Keese, Charles R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Animals Biological and medical sciences Biosensing Techniques Biosensors Biotechnology Cattle Cell Adhesion Cell Movement Cells, Cultured - cytology Cells, Cultured - physiology Cellular biology Electrophysiology - instrumentation Electrophysiology - methods Endothelium, Vascular - cytology Endothelium, Vascular - physiology Fundamental and applied biological sciences. Psychology Macrophages - cytology Macrophages - physiology Male Mammals Methods. Procedures. Technologies Mice Prostatic Neoplasms Rats Sensors Tumor Cells, Cultured Various methods and equipments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An electrical biosensor is described that can continuously track morphological changes of adherent cells providing quantitative data from both sparse and confluent cultures. The method is capable of detecting vertical motion of cells of the order of 1 nm, much below the resolution of an optical microscope.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/366591a0