(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 1993-12, Vol.36 (25), p.4121-4123
Hauptverfasser:	Gaster, Laramie M, Jennings, Andrew J, Joiner, Graham F, King, Frank D, Mulholland, Keith R, Rahman, Shirley K, Starr, Susannah, Wyman, Paul A, Wardle, Kay A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemistry Dioxanes - chemical synthesis Dioxanes - pharmacology Exact sciences and technology Guinea Pigs Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Metoclopramide - analogs & derivatives Muscle Contraction - drug effects Organic chemistry Piperidines - chemical synthesis Piperidines - pharmacology Preparations and properties Receptors, Serotonin - metabolism Serotonin Antagonists - chemical synthesis Serotonin Antagonists - pharmacology Structure-Activity Relationship
Online-Zugang:	Volltext
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