A monoclonal antibody that recognizes an Ly-6-linked antigen inhibits the generation of functionally active T cell subsets

A monoclonal antibody (mAb) generated against the chemically-induced BALB/c Meth A sarcoma, designated HD42, reacts in cytotoxic tests with Meth A as well as with BALB/c peripheral lymph node cells and mitogen-activated spleen cells. The antigen was detected by FACS analysis on BALB/c spleen and lym...

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Veröffentlicht in:	The Journal of immunology (1950) 1985-07, Vol.135 (1), p.63-72
Hauptverfasser:	Flood, PM, Murphy, DB, Horowitz, M, LeClair, KP, Smith, FR, Stockert, E, Palladino, MA, Jr, DeLeo, AB
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - analysis Antibodies, Monoclonal - physiology Antibody Specificity Antigens, Surface - analysis Antigens, Surface - immunology Applied sciences Binding, Competitive Concanavalin A - pharmacology Exact sciences and technology Hemolytic Plaque Technique Interleukin-2 - physiology Isoantibodies - analysis Isoantibodies - physiology Lymphocyte Activation Lymphocyte Culture Test, Mixed Mice Mice, Inbred BALB C Mice, Inbred C57BL Other techniques and industries Stem Cells - immunology T-Lymphocytes - classification T-Lymphocytes - immunology T-Lymphocytes - physiology Tumor Necrosis Factor Receptor Superfamily, Member 7
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