The Effect of Cannabidiol on Mouse Hepatic Microsomal Cytochrome P450-Dependent Anandamide Metabolism

Anandamide (arachidonylethanolamide) has been identified as a brain constituent that selectively binds to the cannabinoid receptor and possesses cannabimimetic activity. Cytochromes P450 catalyze the oxidation of arachidonic acid to several metabolites possessing very potent pharmacological activity...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 1993-12, Vol.197 (2), p.740-746
Hauptverfasser:	Bornheim, L.M., Kim, K.Y., Chen, B.L., Correia, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - metabolism Amidohydrolases Analytical, structural and metabolic biochemistry Animals Arachidonic Acids Biological and medical sciences Biotransformation Calcium Channel Blockers - metabolism Cannabidiol - pharmacology Chromatography, High Pressure Liquid Cytochrome P-450 Enzyme System - drug effects Cytochrome P-450 Enzyme System - metabolism Endocannabinoids Fatty Acids, Unsaturated - metabolism Fundamental and applied biological sciences. Psychology Intermediary metabolites. Miscellaneous Male Mice Mice, Inbred Strains Microsomes, Liver - drug effects Microsomes, Liver - enzymology Mixed Function Oxygenases - metabolism Other biological molecules Polyunsaturated Alkamides Spectrophotometry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!