Higher Production of Tumor Necrosis Factor (TNF) Elicited by a Biological Response Modifier (BRM) in Aging Mice

We investigated age-related changes in the capacity for tumor necrosis factor (TNF) production in young and aged inbred C3H/He mice by injecting them with OK-432, a biological response modifier (BRM). An intravenous injection of 0.4mg of OK-432 was found to induce TNF production and two consecutive...

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Veröffentlicht in:Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 1993/10/15, Vol.48(4), pp.852-858
Hauptverfasser: HAN, Di, HOSOKAWA, Tomohide, AOIKE, Akira, KAWAI, Keiichi
Format: Artikel
Sprache:eng ; jpn
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