Effect of Hydroxymethylglutaryl-CoA Reductase Inhibitors on the Functional Properties of Erythrocyte Membranes

We studied 56 patients affected by primary hypercholesterolemia treated with placebo for 1 month and with simvastatin (20 mg/day) or pravastatin (20 mg/day) for 6 months during a double-blind clinical trial. At 1-month intervals we determined the following parameters in the serum: total and HDL chol...

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Veröffentlicht in:	Experimental and molecular pathology 1993-08, Vol.59 (1), p.51-57
Hauptverfasser:	Rabini, Rosa Anna, Polenta, Mauro, Staffolani, Roberto, Tocchini, Massimo, Signore, Roberto, Testa, Ivano, Mazzanti, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cholesterol - blood Erythrocyte Membrane - drug effects Female General and cellular metabolism. Vitamins Heterozygote Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Hyperlipoproteinemia Type II - blood Hyperlipoproteinemia Type II - drug therapy Hyperlipoproteinemia Type II - metabolism Lipids - blood Lovastatin - analogs & derivatives Lovastatin - therapeutic use Male Medical sciences Membrane Fluidity - drug effects Membrane Lipids - blood Pharmacology. Drug treatments Pravastatin - pharmacology Pravastatin - therapeutic use Simvastatin Sodium-Potassium-Exchanging ATPase - blood
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