Metabolite channeling: A phosphorylcreatine shuttle to mediate high energy phosphate transport between sperm mitochondrion and tail

Energy utilization by the flagellum of motile sea urchin sperm is tightly coupled to the rate of energy production by the mitochondrion. This tight coupling depends upon the transport of high energy phosphate ( −P) from mitochondrion to axoneme, which we propose to be mediated by a phosphorylcreatin...

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Veröffentlicht in:	Cell 1985-05, Vol.41 (1), p.325-334
Hauptverfasser:	Tombes, Robert M., Shapiro, Bennett M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Creatine Kinase - antagonists & inhibitors Creatine Kinase - metabolism Dinitrofluorobenzene - pharmacology Energy Metabolism Exact sciences and technology Isoenzymes Male Mitochondria - metabolism Other techniques and industries Oxygen Consumption Phosphates - metabolism Phosphocreatine - metabolism Sea Urchins - metabolism Sperm Motility Sperm Tail - metabolism Spermatozoa - metabolism Spermatozoa - physiology Spermatozoa - ultrastructure
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