Response with combined modality treatment in childhood rhabdomyosarcoma

Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along wit...

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Veröffentlicht in:Journal of surgical oncology 1993-12, Vol.54 (4), p.243-245
Hauptverfasser: Raje, Noopur S., Rao, Suchitra R., Vaidya, Sucheta J., Shah, Rajesh V., Nair, Chandrika N., Pai, Suresh K., Kurkure, Purna A., Pande, Subodhchandra C., Desai, Prafulla B., Advani, Suresh H.
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container_end_page 245
container_issue 4
container_start_page 243
container_title Journal of surgical oncology
container_volume 54
creator Raje, Noopur S.
Rao, Suchitra R.
Vaidya, Sucheta J.
Shah, Rajesh V.
Nair, Chandrika N.
Pai, Suresh K.
Kurkure, Purna A.
Pande, Subodhchandra C.
Desai, Prafulla B.
Advani, Suresh H.
description Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc.
doi_str_mv 10.1002/jso.2930540411
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subjects Adolescent
Biological and medical sciences
Child
Child, Preschool
Combined Modality Therapy
Diseases of the osteoarticular system
Female
Humans
Male
Medical sciences
Remission Induction
Rhabdomyosarcoma - therapy
Treatment Outcome
Tumors of striated muscle and skeleton
title Response with combined modality treatment in childhood rhabdomyosarcoma
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