Response with combined modality treatment in childhood rhabdomyosarcoma
Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along wit...
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Veröffentlicht in: | Journal of surgical oncology 1993-12, Vol.54 (4), p.243-245 |
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container_title | Journal of surgical oncology |
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creator | Raje, Noopur S. Rao, Suchitra R. Vaidya, Sucheta J. Shah, Rajesh V. Nair, Chandrika N. Pai, Suresh K. Kurkure, Purna A. Pande, Subodhchandra C. Desai, Prafulla B. Advani, Suresh H. |
description | Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc. |
doi_str_mv | 10.1002/jso.2930540411 |
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All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930540411</identifier><identifier>PMID: 8255086</identifier><identifier>CODEN: JSONAU</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Biological and medical sciences ; Child ; Child, Preschool ; Combined Modality Therapy ; Diseases of the osteoarticular system ; Female ; Humans ; Male ; Medical sciences ; Remission Induction ; Rhabdomyosarcoma - therapy ; Treatment Outcome ; Tumors of striated muscle and skeleton</subject><ispartof>Journal of surgical oncology, 1993-12, Vol.54 (4), p.243-245</ispartof><rights>Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3641-d43d8efaef341140169c92b671963320c828e85e692b9f3bcaed9f063cba7b9d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930540411$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930540411$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3885495$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8255086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raje, Noopur S.</creatorcontrib><creatorcontrib>Rao, Suchitra R.</creatorcontrib><creatorcontrib>Vaidya, Sucheta J.</creatorcontrib><creatorcontrib>Shah, Rajesh V.</creatorcontrib><creatorcontrib>Nair, Chandrika N.</creatorcontrib><creatorcontrib>Pai, Suresh K.</creatorcontrib><creatorcontrib>Kurkure, Purna A.</creatorcontrib><creatorcontrib>Pande, Subodhchandra C.</creatorcontrib><creatorcontrib>Desai, Prafulla B.</creatorcontrib><creatorcontrib>Advani, Suresh H.</creatorcontrib><title>Response with combined modality treatment in childhood rhabdomyosarcoma</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Remission Induction</subject><subject>Rhabdomyosarcoma - therapy</subject><subject>Treatment Outcome</subject><subject>Tumors of striated muscle and skeleton</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1v1DAQxa0K1C6lV26VckDcsoxjx7GPaNUuH4VWUATiYjn2ROs2ibd2VmX_e4x2tRUnTiPN_N6bp0fIKwpzClC9vUthXikGNQdO6RGZUVCiVKDkMzLLQFXyRsEJeZHSHQAoJfgxOZZVXYMUM7L8imkdxoTFo59WhQ1D60d0xRCc6f20LaaIZhpwnAo_Fnble7cKwRVxZVoXhm1IJmaReUmed6ZPeLafp-T75cXt4n15db38sHh3VVomOC0dZ05iZ7BjOS0HKpRVVSsaqgRjFVhZSZQ1irxUHWutQac6EMy2pmmVY6fkzc53HcPDBtOkB58s9r0ZMWySbgSFWjCVwfkOtDGkFLHT6-gHE7eagv7bnM7N6afmsuB877xpB3QHfF9Vvr_e302ypu-iGa1PB4xJWXNVZ0ztsEff4_Y_T_XHb9f_RCh3Wp8m_H3QmnivRcOaWv_4stSff_KbxadfN_qW_QGy5pcC</recordid><startdate>199312</startdate><enddate>199312</enddate><creator>Raje, Noopur S.</creator><creator>Rao, Suchitra R.</creator><creator>Vaidya, Sucheta J.</creator><creator>Shah, Rajesh V.</creator><creator>Nair, Chandrika N.</creator><creator>Pai, Suresh K.</creator><creator>Kurkure, Purna A.</creator><creator>Pande, Subodhchandra C.</creator><creator>Desai, Prafulla B.</creator><creator>Advani, Suresh H.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199312</creationdate><title>Response with combined modality treatment in childhood rhabdomyosarcoma</title><author>Raje, Noopur S. ; Rao, Suchitra R. ; Vaidya, Sucheta J. ; Shah, Rajesh V. ; Nair, Chandrika N. ; Pai, Suresh K. ; Kurkure, Purna A. ; Pande, Subodhchandra C. ; Desai, Prafulla B. ; Advani, Suresh H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3641-d43d8efaef341140169c92b671963320c828e85e692b9f3bcaed9f063cba7b9d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Combined Modality Therapy</topic><topic>Diseases of the osteoarticular system</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Remission Induction</topic><topic>Rhabdomyosarcoma - therapy</topic><topic>Treatment Outcome</topic><topic>Tumors of striated muscle and skeleton</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raje, Noopur S.</creatorcontrib><creatorcontrib>Rao, Suchitra R.</creatorcontrib><creatorcontrib>Vaidya, Sucheta J.</creatorcontrib><creatorcontrib>Shah, Rajesh V.</creatorcontrib><creatorcontrib>Nair, Chandrika N.</creatorcontrib><creatorcontrib>Pai, Suresh K.</creatorcontrib><creatorcontrib>Kurkure, Purna A.</creatorcontrib><creatorcontrib>Pande, Subodhchandra C.</creatorcontrib><creatorcontrib>Desai, Prafulla B.</creatorcontrib><creatorcontrib>Advani, Suresh H.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Raje, Noopur S.</au><au>Rao, Suchitra R.</au><au>Vaidya, Sucheta J.</au><au>Shah, Rajesh V.</au><au>Nair, Chandrika N.</au><au>Pai, Suresh K.</au><au>Kurkure, Purna A.</au><au>Pande, Subodhchandra C.</au><au>Desai, Prafulla B.</au><au>Advani, Suresh H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Response with combined modality treatment in childhood rhabdomyosarcoma</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1993-12</date><risdate>1993</risdate><volume>54</volume><issue>4</issue><spage>243</spage><epage>245</epage><pages>243-245</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><coden>JSONAU</coden><abstract>Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>8255086</pmid><doi>10.1002/jso.2930540411</doi><tpages>3</tpages></addata></record> |
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subjects | Adolescent Biological and medical sciences Child Child, Preschool Combined Modality Therapy Diseases of the osteoarticular system Female Humans Male Medical sciences Remission Induction Rhabdomyosarcoma - therapy Treatment Outcome Tumors of striated muscle and skeleton |
title | Response with combined modality treatment in childhood rhabdomyosarcoma |
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