Substance P mechanisms of the spinal cord related to vasomotor tone in the spontaneously hypertensive rat

This report deals with substance P (SP) mechanisms involved in regulation of vasomotor tone at the spinal cord levels in normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). Our results indicate the following. (1) Intrathecal injections of the SP antagonist, d-Pro 4, d-Trp 7.9-...

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Veröffentlicht in:	Brain research 1985-05, Vol.334 (1), p.105-116
Hauptverfasser:	Takano, Yukio, Sawyer, William B., Loewy, Arthur D.
Format:	Artikel
Sprache:	eng
Schlagworte:	[ 3H]substance P binding Animals Arterial hypertension. Arterial hypotension Autonomic Fibers, Preganglionic - physiology Biological and medical sciences Blood and lymphatic vessels Blood Pressure blood pressure regulation Cardiology. Vascular system d-Pro 4, d-Trp 7,9-substance P 4–11 Experimental diseases gamma-Aminobutyric Acid - physiology Heart Rate hypertension intermediolateral cell column Male Medical sciences Nervous system involvement in other diseases. Miscellaneous Neurology Rats Rats, Inbred SHR Rats, Inbred WKY Spinal Cord - physiology spontaneously hypertensive rat substance P Substance P - analogs & derivatives Substance P - pharmacology Substance P - physiology Vasomotor System - physiology vasomotor tone
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