Myocardial force-frequency defect in mitral regurgitation heart failure is reversed by forskolin

Postoperative ejection phase parameters and patient survival rates for mitral valve replacement surgery are considerably lower than for similar aortic valve surgery. While chordal transection probably is the major contributor to the lowered values, there is also evidence for decreased preoperative m...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1993-12, Vol.88 (6), p.2700-2704
Hauptverfasser:	MULIERI, L. A, LEAVITT, B. J, MARTIN, B. J, HAEBERLE, J. R, ALPERT, N. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiology. Vascular system Colforsin - pharmacology Electric Stimulation Endocardial and cardiac valvular diseases Female Heart Heart Failure - drug therapy Heart Failure - etiology Heart Failure - physiopathology Heart Valve Prosthesis Humans In Vitro Techniques Male Medical sciences Middle Aged Mitral Valve Mitral Valve Insufficiency - complications Mitral Valve Insufficiency - physiopathology Mitral Valve Insufficiency - surgery Myocardial Contraction - drug effects Myocardial Contraction - physiology Stroke Volume
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