Individual Tumors of Multifocal EB Virus--Induced Malignant Lymphomas in Tamarins Arise from Different B-Cell Clones

Cotton-top tamarins were inoculated with sufficient Epstein-Barr virus to induce multiple tumors in each animal within 14 to 21 days. The tumors consisted of large-cell lymphomas that contained multiple copies of the Epstein-Barr virus genome and generated Epstein-Barr virus--carrying cell lines sho...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1985-05, Vol.228 (4700), p.722-724
Hauptverfasser:	Cleary, M. L., Epstein, M. A., Finerty, S., Dorfman, R. F., Bornkamm, G. W., Kirkwood, J. K., Morgan, A. J., Sklar, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B lymphocytes B-Lymphocytes - microbiology Burkitt Lymphoma - genetics Burkitt Lymphoma - microbiology Cancer Cancer research Cell Line Cell lines DNA, Neoplasm - genetics Epstein Barr virus infections Epstein-Barr virus Genomes Heart Transplantation Herpesvirus 4, Human Humans Inoculation Lesions Lymphoma Neoplasms, Experimental - genetics Neoplasms, Experimental - microbiology Nucleic Acid Hybridization Observations Oncology, Experimental Saguinus Tumor cell line Tumors Viral research Virus research Viruses
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