Management of Chronic Myeloid Leukemia in Chronic Phase with Autologous Stem Cell Transplantation and Alpha-2 Interferon: Cytogenetic and Clinical Results

Forty-eight patients with chronic myeloid leukemia (CML) in chronic phase (CP) were treated by autologous stem cells transplantation (ASCT) and α Interferon (IFN) with three approaches: 1) ASCT at diagnosis followed by IFN, 2) ASCT post IFN with cells collected after an interval from IFN discontinua...

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Veröffentlicht in:	Leukemia & lymphoma 1993, Vol.11 (s1), p.281-291
Hauptverfasser:	Alimena, Giuliana, Meloni, Giovanna, De Cuia, M. Rosaria, Rondinelli, M. Beatrice, Coco, Francesco Lo, Montefusco, Enrico, Mancini, Marco, Pinto, Rita, Nanni, Mauro, Cedrone, Michele, Fabritiis, Paolo De, Mandelli, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blood Component Transfusion Blood Transfusion, Autologous Bone Marrow - pathology Bone Marrow Purging Bone Marrow Transplantation Combined Modality Therapy Female Hematopoietic Stem Cell Transplantation Humans Hydroxyurea - therapeutic use Immunologic Factors - therapeutic use Interferon alpha-2 Interferon-alpha - therapeutic use Italy - epidemiology Karyotyping Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - mortality Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy Leukemia, Myeloid, Chronic-Phase - genetics Leukemia, Myeloid, Chronic-Phase - mortality Leukemia, Myeloid, Chronic-Phase - pathology Leukemia, Myeloid, Chronic-Phase - therapy Male Middle Aged Neoplastic Stem Cells - ultrastructure Prospective Studies Recombinant Proteins Remission Induction Survival Rate Treatment Outcome
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