Selective localization and rotational immobilization of univalent cations on quadruplex DNA

The quadruplex structure of the oligomer d(T2G4T) is more stable in the presence of K+ than in the presence of Na+. This enhanced stability correlates with the preferential binding of K+ to a small number of specific sites on the quadruplex. In contrast, Na+ and K+ compete on an equal footing for at...

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Veröffentlicht in:	Biochemistry (Easton) 1993-12, Vol.32 (48), p.13130-13137
Hauptverfasser:	Xu, Qiuwei, Deng, Hong, Braunlin, William H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Cations, Monovalent DNA - chemistry Dna, deoxyribonucleoproteins Fundamental and applied biological sciences. Psychology Magnetic Resonance Spectroscopy Motion Nucleic Acid Conformation Nucleic acids Oligodeoxyribonucleotides - chemistry Potassium - chemistry Sodium - chemistry
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