Structural study of the sugar chains of human leukocyte common antigen CD45

The leukocyte cell surface glycoprotein CD45 is a protein tyrosine phosphatase and is involved in signal transduction mediated by the T cell antigen receptor. The asparagine-linked sugar chains were released as oligosaccharides from purified CD45 by hydrazinolysis. Approximately 6 mol of sugar chain...

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Veröffentlicht in:	Biochemistry (Easton) 1993-11, Vol.32 (47), p.12694-12704
Hauptverfasser:	Sato, Takeshi, Furukawa, Kiyoshi, Autero, Matti, Gahmberg, Carl G, Kobata, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Asparagine - chemistry beta-Galactosidase - metabolism Biological and medical sciences Carbohydrate Conformation Carbohydrate Sequence Chromatography, Affinity Electrophoresis, Paper Fundamental and applied biological sciences. Psychology Fundamental immunology Glycoside Hydrolases - metabolism Humans Immunobiology Leukocyte Common Antigens - chemistry Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Molecular Sequence Data Oligosaccharides - chemistry Oligosaccharides - isolation & purification Oligosaccharides - metabolism Sialic Acids T-Lymphocytes - immunology
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