The three-dimensional morphology of afferent terminal fields in the rat dentate gyrus: Periodic variation
The laminated afferent terminal fields in the rat dentate gyrus molecular layer exhibit differential histochemical staining properties. Dependent variables (e.g., field geometries, stain intensity) based on this organization can allow evaluation of the effect of independent variables upon the integr...
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| Veröffentlicht in: | Journal of comparative neurology (1911) 1985-04, Vol.234 (3), p.334-343 |
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| container_end_page | 343 |
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| container_issue | 3 |
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| container_title | Journal of comparative neurology (1911) |
| container_volume | 234 |
| creator | King, Michael A. Reep, Roger L. Hunter, Bruce E. Walker, Don W. |
| description | The laminated afferent terminal fields in the rat dentate gyrus molecular layer exhibit differential histochemical staining properties. Dependent variables (e.g., field geometries, stain intensity) based on this organization can allow evaluation of the effect of independent variables upon the integrity of each afferent, but anatomically justifiable procedures for matching measurement regions across animals are necessary. We describe such a procedure and a serendipitous observation on the normal organization of the terminal fields. From a 10 × 10 mediolateral × anteroposterior array of measurement points per animal, it was determined that each afferent field, and the total molecular layer, exhibits periodic variation in width relative to the granule cell layer. Thus, to reduce statistical variability, either a high dependent variable sampling rate, or sampling within a region of naturally low variability, is suggested. Evidence for such a region is presented, and possible consequences of this novel topology of afferentation are discussed. |
| doi_str_mv | 10.1002/cne.902340305 |
| format | Article |
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Dependent variables (e.g., field geometries, stain intensity) based on this organization can allow evaluation of the effect of independent variables upon the integrity of each afferent, but anatomically justifiable procedures for matching measurement regions across animals are necessary. We describe such a procedure and a serendipitous observation on the normal organization of the terminal fields. From a 10 × 10 mediolateral × anteroposterior array of measurement points per animal, it was determined that each afferent field, and the total molecular layer, exhibits periodic variation in width relative to the granule cell layer. Thus, to reduce statistical variability, either a high dependent variable sampling rate, or sampling within a region of naturally low variability, is suggested. 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Psychology ; hippocampus ; Hippocampus - anatomy & histology ; Male ; molecular layer ; morphometry ; Neurons - ultrastructure ; Rats ; Synapses - ultrastructure ; Timm's ; Vertebrates: nervous system and sense organs</subject><ispartof>Journal of comparative neurology (1911), 1985-04, Vol.234 (3), p.334-343</ispartof><rights>Copyright © 1985 Alan R. 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Comp. Neurol</addtitle><description>The laminated afferent terminal fields in the rat dentate gyrus molecular layer exhibit differential histochemical staining properties. Dependent variables (e.g., field geometries, stain intensity) based on this organization can allow evaluation of the effect of independent variables upon the integrity of each afferent, but anatomically justifiable procedures for matching measurement regions across animals are necessary. We describe such a procedure and a serendipitous observation on the normal organization of the terminal fields. From a 10 × 10 mediolateral × anteroposterior array of measurement points per animal, it was determined that each afferent field, and the total molecular layer, exhibits periodic variation in width relative to the granule cell layer. Thus, to reduce statistical variability, either a high dependent variable sampling rate, or sampling within a region of naturally low variability, is suggested. Evidence for such a region is presented, and possible consequences of this novel topology of afferentation are discussed.</description><subject>Afferent Pathways - anatomy & histology</subject><subject>Anatomy</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Central nervous system</subject><subject>computer</subject><subject>Computers</subject><subject>Dendrites - ultrastructure</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>hippocampus</subject><subject>Hippocampus - anatomy & histology</subject><subject>Male</subject><subject>molecular layer</subject><subject>morphometry</subject><subject>Neurons - ultrastructure</subject><subject>Rats</subject><subject>Synapses - ultrastructure</subject><subject>Timm's</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0021-9967</issn><issn>1096-9861</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1vEzEQxS1EVULLkSOSD6i3bf2xttfcUPqFVJUeSjlajnfcGHbXqb1pm_8eR1lFnEAayYf3mzfjeQh9pOSUEsLO3ACnmjBeE07EGzSjRMtKN5K-RbOi00prqd6h9zn_IoRozZtDdMh105SaoXC_BDwuE0DVhh6GHOJgO9zHtFrGLj5ucPTYeg8JhhGPkPqw1X2Ars04DKUXcLIjbotuR8CPm7TOX_AdpBDb4PCzTcGOxfUYHXjbZfgwvUfox-XF_fy6uvl-9W3-9aZyvNaiAkFrzzS3fgGsAcqY9nxBy--0bDVXglvHFZOK1462C640aYTgVAIIL6nnR-hk57tK8WkNeTR9yA66zg4Q19koSRqmis__QFpTqZSWBax2oEsx5wTerFLobdoYSsw2A1MyMPsMCv9pMl4vemj39HT0on-edJud7Xyygwt5j2lWMyG3mNphL6GDzb9nmvntxd8LTAuHPMLrvtOm36bcTQnz8_bKPDyc6_OGXptL_ge-uK4Q</recordid><startdate>19850415</startdate><enddate>19850415</enddate><creator>King, Michael A.</creator><creator>Reep, Roger L.</creator><creator>Hunter, Bruce E.</creator><creator>Walker, Don W.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19850415</creationdate><title>The three-dimensional morphology of afferent terminal fields in the rat dentate gyrus: Periodic variation</title><author>King, Michael A. ; Reep, Roger L. ; Hunter, Bruce E. ; Walker, Don W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3495-e514f293afbe28e1229f3b140396d93753ac3726734c1db3790855316ee5f61f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Afferent Pathways - anatomy & histology</topic><topic>Anatomy</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Central nervous system</topic><topic>computer</topic><topic>Computers</topic><topic>Dendrites - ultrastructure</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>hippocampus</topic><topic>Hippocampus - anatomy & histology</topic><topic>Male</topic><topic>molecular layer</topic><topic>morphometry</topic><topic>Neurons - ultrastructure</topic><topic>Rats</topic><topic>Synapses - ultrastructure</topic><topic>Timm's</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>King, Michael A.</creatorcontrib><creatorcontrib>Reep, Roger L.</creatorcontrib><creatorcontrib>Hunter, Bruce E.</creatorcontrib><creatorcontrib>Walker, Don W.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of comparative neurology (1911)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>King, Michael A.</au><au>Reep, Roger L.</au><au>Hunter, Bruce E.</au><au>Walker, Don W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The three-dimensional morphology of afferent terminal fields in the rat dentate gyrus: Periodic variation</atitle><jtitle>Journal of comparative neurology (1911)</jtitle><addtitle>J. Comp. Neurol</addtitle><date>1985-04-15</date><risdate>1985</risdate><volume>234</volume><issue>3</issue><spage>334</spage><epage>343</epage><pages>334-343</pages><issn>0021-9967</issn><eissn>1096-9861</eissn><coden>JCNEAM</coden><abstract>The laminated afferent terminal fields in the rat dentate gyrus molecular layer exhibit differential histochemical staining properties. Dependent variables (e.g., field geometries, stain intensity) based on this organization can allow evaluation of the effect of independent variables upon the integrity of each afferent, but anatomically justifiable procedures for matching measurement regions across animals are necessary. We describe such a procedure and a serendipitous observation on the normal organization of the terminal fields. 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| ispartof | Journal of comparative neurology (1911), 1985-04, Vol.234 (3), p.334-343 |
| issn | 0021-9967 1096-9861 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Afferent Pathways - anatomy & histology Anatomy Animals Biological and medical sciences Central nervous system computer Computers Dendrites - ultrastructure Fundamental and applied biological sciences. Psychology hippocampus Hippocampus - anatomy & histology Male molecular layer morphometry Neurons - ultrastructure Rats Synapses - ultrastructure Timm's Vertebrates: nervous system and sense organs |
| title | The three-dimensional morphology of afferent terminal fields in the rat dentate gyrus: Periodic variation |
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