The Problem of Partial Competition in the Quantitative Characterization of Interactions by Competitive Binding Assays

Binding expressions are derived and analytical procedures developed for the quantitative characterization of inhibitor binding that is only partially competitive with the interaction between an acceptor and the ligand that is being monitored. Two such situations are considered: (i) that in which the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Analytical biochemistry 1993-08, Vol.213 (1), p.104-110
Hauptverfasser:	Brocklebank, A.M., Sawyer, W.H., Wiley, J.S., Winzor, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - metabolism Affinity Labels Binding Sites Binding, Competitive Biological and medical sciences General pharmacology Humans Kinetics Leukemia, Myelomonocytic, Acute - metabolism Mathematical Computing Medical sciences Models, Biological Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Receptors, Cell Surface - metabolism Thioinosine - analogs & derivatives Thioinosine - metabolism Thionucleosides - metabolism Tritium Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!