Specificity of monoclonal antibodies directed against human and murine class II histocompatibility antigens as analyzed by binding to HLA-deletion mutant cell lines

The specificity of 70 monoclonal anti-Ia monoclonal antibodies (MoAbs) (18 mouse allo-induced and 52 rodent anti-human) was studied with a panel of 17 HLA-deletion mutants that were derived from a single parent line and vary in expression of Ia antigens due to deletion of different subregions of HLA...

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Veröffentlicht in:	Human immunology 1985-04, Vol.12 (4), p.191-211
Hauptverfasser:	Shaw, Stephen, Ziegler, Andreas, DeMars, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - classification Antibody Specificity Antigens, Heterophile - genetics Binding Sites, Antibody Cell Line Cross Reactions Enzyme-Linked Immunosorbent Assay Genes, MHC Class II Genotype Haploidy Histocompatibility Antigens Class II - classification Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology HLA Antigens - classification HLA Antigens - genetics HLA Antigens - immunology Humans Lymphocytes, Null - immunology Mice Mutation
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