Superantigens —remnants of a past process?

Superantigens (SAg) bind simultaneously to T-cell receptors (TcR) and major histocompatibility complex (MHC) class II molecules to activate up to 20% of all peripheral T cells via the TcR V beta region. Their action defines an extremely potent form of TcR triggering in which the vast amino acid dive...

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Veröffentlicht in:	Research in immunology (Paris) 1993, Vol.144 (3), p.188-193
Hauptverfasser:	Fraser, J.D., Hudson, K.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites - immunology Enterotoxins - immunology Epitopes - immunology Histocompatibility Antigens Class II - immunology Humans Models, Molecular Receptors, Antigen, T-Cell, alpha-beta - immunology Staphylococcus aureus - immunology Superantigens - immunology T-Lymphocytes - immunology
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