Treatment of Human Melanocytes and S91 Melanoma Cells with the DNA Repair Enzyme T4 Endonuclease V Enhances Melanogenesis After Ultraviolet Irradiation

Tanning is a protective response of ultraviolet (UV)-irradiated skin that decreases damage from subsequent sun exposures by increasing the epidermal content of melanin, a brown-black pigment that absorbs light energy throughout the UV and visible portions of the electromagnetic spectrum. The melanin...

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Veröffentlicht in:	Journal of investigative dermatology 1993-11, Vol.101 (5), p.666-672
Hauptverfasser:	Gilchrest, Barbara A, Zhai, Sen, Eller, Mark S, Yarosh, Daniel B, Yaar, Mina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Division - radiation effects Cells, Cultured Deoxyribonuclease (Pyrimidine Dimer) Dihydroxyphenylalanine - metabolism DNA Repair Endodeoxyribonucleases - metabolism endonuclease Fundamental and applied biological sciences. Psychology Humans irradiation melanin Melanins - analysis Melanins - biosynthesis melanocytes Melanocytes - metabolism Melanocytes - radiation effects Melanoma, Experimental - metabolism Molecular and cellular biology Molecular genetics Mutagenesis. Repair tanning Tumor Cells, Cultured tyrosinase Ultraviolet Rays Viral Proteins
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