Cranial MR Imaging and Cerebral 99mTc HM-Pao-Spect in Patients with Subacute or Chronic Severe Closed Head Injury and Normal CT examinations
Eighteen patients in the subacute or chronic state following severe closed head injury with normal cranial CT scans were examined by MR and 99mTc HM-PAO SPECT. Correlations were sought between these 2 imaging modalities and the clinical outcome, as defined by the Glasgow Outcome Scale (GOS) score. B...
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| Veröffentlicht in: | Acta radiologica (1987) 1993-11, Vol.34 (6), p.593-599 |
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| container_title | Acta radiologica (1987) |
| container_volume | 34 |
| creator | Prayer, Lucas Wimberger, D. Oder, W. Kramer, J. Schindler, E. Podrekam, I. Imhof, H. |
| description | Eighteen patients in the subacute or chronic state following severe closed head injury with normal cranial CT scans were examined by MR and 99mTc HM-PAO SPECT. Correlations were sought between these 2 imaging modalities and the clinical outcome, as defined by the Glasgow Outcome Scale (GOS) score. Both MR and SPECT revealed cerebral damage in all patients examined but structural and functional alterations did not coincide topographically in 64.9% of lesions. Nevertheless, complementary injury patterns suggesting poor recovery were found; cortical contusions and diffuse axonal injury (MR) in conjunction with cortical and thalamic hypoperfusion (SPECT) were noticed in 8 out of 12 patients with unfavorable outcome (GOS = III and IV). the synthesis of MR and SPECT information clearly enhanced the ability both to accurately assess posttraumatic brain damage and to improve patients' outcome prediction. |
| doi_str_mv | 10.3109/02841859309175414 |
| format | Article |
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Nevertheless, complementary injury patterns suggesting poor recovery were found; cortical contusions and diffuse axonal injury (MR) in conjunction with cortical and thalamic hypoperfusion (SPECT) were noticed in 8 out of 12 patients with unfavorable outcome (GOS = III and IV). the synthesis of MR and SPECT information clearly enhanced the ability both to accurately assess posttraumatic brain damage and to improve patients' outcome prediction.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Brain - diagnostic imaging</subject><subject>Brain - pathology</subject><subject>Brain Injuries - diagnosis</subject><subject>Brain Injuries - diagnostic imaging</subject><subject>Female</subject><subject>Head Injuries, Closed - diagnosis</subject><subject>Head Injuries, Closed - diagnostic imaging</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Organotechnetium Compounds</subject><subject>Oximes</subject><subject>Technetium Tc 99m Exametazime</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Tomography, X-Ray Computed</subject><issn>0284-1851</issn><issn>1600-0455</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkctOwzAURC0EgvL4ABZIXrEL2LGdxGKFIqCVeIl2H9nJDXWV2MVOePwDH40L3bG60p3RkWYGoVNKLhgl8pKkBaeFkIxImgtO-Q6a0IyQhHAhdtFkoyfRQA_QYQgrQmiaC7qP9ouUk0KKCfouvbJGdfjhBc969WrsK1a2wSV40D7-pewXNZ4-JM_KJfM11AM2Fj-rwYAdAv4wwxLPR63qcQDsPC6X3llT4zm8RwQuOxegwVNQDZ7Z1ei_fvGPzvcRXi4wfKre2IhzNhyjvVZ1AU629wgtbm8W5TS5f7qbldf3iaFEiASyHACYAKViDt5Q3XLW5g3XWhciz9pUMiF0TjlLs5SIlKVS57GkghVU1OwInf9h1969jRCGqjehhq5TFtwYqjwjgjBJo_Fsaxx1D0219qZX_qvathf1qz_d2HYTaAmqG5a18lCt3OhtzFBRUm2mqv5NxX4A85mCwg</recordid><startdate>199311</startdate><enddate>199311</enddate><creator>Prayer, Lucas</creator><creator>Wimberger, D.</creator><creator>Oder, W.</creator><creator>Kramer, J.</creator><creator>Schindler, E.</creator><creator>Podrekam, I.</creator><creator>Imhof, H.</creator><general>Informa UK Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199311</creationdate><title>Cranial MR Imaging and Cerebral 99mTc HM-Pao-Spect in Patients with Subacute or Chronic Severe Closed Head Injury and Normal CT examinations</title><author>Prayer, Lucas ; Wimberger, D. ; Oder, W. ; Kramer, J. ; Schindler, E. ; Podrekam, I. ; Imhof, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i1055-e67eee35eaa8244d1bf43f7d4bbb8576f29355b7143262052329b793083815c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Brain - diagnostic imaging</topic><topic>Brain - pathology</topic><topic>Brain Injuries - diagnosis</topic><topic>Brain Injuries - diagnostic imaging</topic><topic>Female</topic><topic>Head Injuries, Closed - diagnosis</topic><topic>Head Injuries, Closed - diagnostic imaging</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Organotechnetium Compounds</topic><topic>Oximes</topic><topic>Technetium Tc 99m Exametazime</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Prayer, Lucas</creatorcontrib><creatorcontrib>Wimberger, D.</creatorcontrib><creatorcontrib>Oder, W.</creatorcontrib><creatorcontrib>Kramer, J.</creatorcontrib><creatorcontrib>Schindler, E.</creatorcontrib><creatorcontrib>Podrekam, I.</creatorcontrib><creatorcontrib>Imhof, H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta radiologica (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Prayer, Lucas</au><au>Wimberger, D.</au><au>Oder, W.</au><au>Kramer, J.</au><au>Schindler, E.</au><au>Podrekam, I.</au><au>Imhof, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cranial MR Imaging and Cerebral 99mTc HM-Pao-Spect in Patients with Subacute or Chronic Severe Closed Head Injury and Normal CT examinations</atitle><jtitle>Acta radiologica (1987)</jtitle><addtitle>Acta Radiol</addtitle><date>1993-11</date><risdate>1993</risdate><volume>34</volume><issue>6</issue><spage>593</spage><epage>599</epage><pages>593-599</pages><issn>0284-1851</issn><eissn>1600-0455</eissn><abstract>Eighteen patients in the subacute or chronic state following severe closed head injury with normal cranial CT scans were examined by MR and 99mTc HM-PAO SPECT. Correlations were sought between these 2 imaging modalities and the clinical outcome, as defined by the Glasgow Outcome Scale (GOS) score. Both MR and SPECT revealed cerebral damage in all patients examined but structural and functional alterations did not coincide topographically in 64.9% of lesions. Nevertheless, complementary injury patterns suggesting poor recovery were found; cortical contusions and diffuse axonal injury (MR) in conjunction with cortical and thalamic hypoperfusion (SPECT) were noticed in 8 out of 12 patients with unfavorable outcome (GOS = III and IV). the synthesis of MR and SPECT information clearly enhanced the ability both to accurately assess posttraumatic brain damage and to improve patients' outcome prediction.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>8240895</pmid><doi>10.3109/02841859309175414</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0284-1851 |
| ispartof | Acta radiologica (1987), 1993-11, Vol.34 (6), p.593-599 |
| issn | 0284-1851 1600-0455 |
| language | eng |
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| source | MEDLINE; Taylor & Francis:Master (3349 titles) |
| subjects | Adolescent Adult Brain - diagnostic imaging Brain - pathology Brain Injuries - diagnosis Brain Injuries - diagnostic imaging Female Head Injuries, Closed - diagnosis Head Injuries, Closed - diagnostic imaging Humans Magnetic Resonance Imaging Male Middle Aged Organotechnetium Compounds Oximes Technetium Tc 99m Exametazime Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed |
| title | Cranial MR Imaging and Cerebral 99mTc HM-Pao-Spect in Patients with Subacute or Chronic Severe Closed Head Injury and Normal CT examinations |
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