Primary Human Herpesvirus 6 Infection in an Adult
To the Editor: Akashi et al. (July 15 issue) 1 reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue) 2 detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants w...
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Veröffentlicht in: | The New England journal of medicine 1993-12, Vol.329 (24), p.1817-1819 |
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container_title | The New England journal of medicine |
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creator | Morris, D J |
description | To the Editor:
Akashi et al. (July 15 issue)
1
reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)
2
detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus
1
,
3
. The authors interpreted the serologic findings (IgG seroconversion with no IgM . . . |
doi_str_mv | 10.1056/NEJM199312093292416 |
format | Article |
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Akashi et al. (July 15 issue)
1
reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)
2
detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus
1
,
3
. The authors interpreted the serologic findings (IgG seroconversion with no IgM . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199312093292416</identifier><identifier>PMID: 8232498</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Adult ; Graft vs Host Disease - microbiology ; Herpesviridae Infections - diagnosis ; Herpesviridae Infections - microbiology ; Herpesvirus 6, Human - isolation & purification ; Humans ; Infectious Mononucleosis - microbiology ; Lung Diseases - microbiology</subject><ispartof>The New England journal of medicine, 1993-12, Vol.329 (24), p.1817-1819</ispartof><rights>Copyright © 1993 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-e910e7a19e459c8d489c2f55b5c3f2854c961638ab8bb0f38729c0af75873d953</citedby><cites>FETCH-LOGICAL-c538t-e910e7a19e459c8d489c2f55b5c3f2854c961638ab8bb0f38729c0af75873d953</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199312093292416$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199312093292416$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,780,784,2758,2759,26102,27923,27924,52381,54063,64386</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8232498$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morris, D J</creatorcontrib><title>Primary Human Herpesvirus 6 Infection in an Adult</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Akashi et al. (July 15 issue)
1
reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)
2
detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus
1
,
3
. The authors interpreted the serologic findings (IgG seroconversion with no IgM . . .</description><subject>Adult</subject><subject>Graft vs Host Disease - microbiology</subject><subject>Herpesviridae Infections - diagnosis</subject><subject>Herpesviridae Infections - microbiology</subject><subject>Herpesvirus 6, Human - isolation & purification</subject><subject>Humans</subject><subject>Infectious Mononucleosis - microbiology</subject><subject>Lung Diseases - microbiology</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLw0AUhQdRaq3-AhGyciPReT-WpVRTqY-FrofJZAZSMkmdSQT_vZEUV-LdnMV3zoF7ALhE8BZBxu-e149PSCmCMFQEK0wRPwJzxAjJKYX8GMwhxDKnQpFTcJbSDo6HqJqBmcQEUyXnAL3GOpj4lRVDMG1WuLh36bOOQ8p4tmm9s33dtVndZiNdVkPTn4MTb5rkLg66AO_367dVkW9fHjar5Ta3jMg-dwpBJwxSjjJlZUWlstgzVjJLPJaMWsURJ9KUsiyhJ1JgZaHxgklBKsXIAlxPvfvYfQwu9TrUybqmMa3rhqQFh1RSKEYjmYw2dilF5_V--kkjqH-G0n8MNaauDvVDGVz1mzksM_KbiYeQdOt24d-2bwqObUY</recordid><startdate>19931209</startdate><enddate>19931209</enddate><creator>Morris, D J</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19931209</creationdate><title>Primary Human Herpesvirus 6 Infection in an Adult</title><author>Morris, D J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-e910e7a19e459c8d489c2f55b5c3f2854c961638ab8bb0f38729c0af75873d953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adult</topic><topic>Graft vs Host Disease - microbiology</topic><topic>Herpesviridae Infections - diagnosis</topic><topic>Herpesviridae Infections - microbiology</topic><topic>Herpesvirus 6, Human - isolation & purification</topic><topic>Humans</topic><topic>Infectious Mononucleosis - microbiology</topic><topic>Lung Diseases - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morris, D J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morris, D J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary Human Herpesvirus 6 Infection in an Adult</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1993-12-09</date><risdate>1993</risdate><volume>329</volume><issue>24</issue><spage>1817</spage><epage>1819</epage><pages>1817-1819</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Akashi et al. (July 15 issue)
1
reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)
2
detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus
1
,
3
. The authors interpreted the serologic findings (IgG seroconversion with no IgM . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>8232498</pmid><doi>10.1056/NEJM199312093292416</doi><tpages>3</tpages></addata></record> |
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language | eng |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
subjects | Adult Graft vs Host Disease - microbiology Herpesviridae Infections - diagnosis Herpesviridae Infections - microbiology Herpesvirus 6, Human - isolation & purification Humans Infectious Mononucleosis - microbiology Lung Diseases - microbiology |
title | Primary Human Herpesvirus 6 Infection in an Adult |
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