Astrocytic hypertrophy: An important pathological feature of chronic experimental autoimmune encephalitis in aged rats

Experimental autoimmune encephalomyelitis (EAE) was induced in young (2–3 month old), middle-aged (12–13 month old) and geriatric (24–26 month old) Lewis (JC) rats by active immunisation with myelin basic protein (MBP) in complete Freund's adjuvant (CFA). It was found that aged Lewis (JC) rats...

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Veröffentlicht in:	Journal of neuroimmunology 1993-11, Vol.48 (2), p.121-134
Hauptverfasser:	Ludowyk, Patricia A., Hughes, Wendy, Hugh, Andrew, Willenberg, David O., Rockett, Kirk A., Parish, Christopher R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Animals Astrocytes - pathology Astrocytic hypertrophy Biological and medical sciences Encephalomyelitis, Autoimmune, Experimental - pathology Experimental and animal immunopathology. Animal models Experimental autoimmune encephalomyelitis Female Hypertrophy Immunopathology Male Medical sciences Myelin Basic Protein - immunology Rats Rats, Inbred Lew Spinal Cord - pathology
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