Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA)

Cell movement and cell-type-specific gene expression during Dictyostelium development are regulated by cAMP, which functions both as an extracellular hormone-like signal and an intracellular second messenger. Previous data indicated that aca- mutants, which lack adenylyl cyclase activity, fail to ag...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genes & development 1993-11, Vol.7 (11), p.2172-2180
Hauptverfasser:	PITT, G. S, BRANDT, R, LIN, K. C, DEVREOTES, P. N, SCHAAP, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - genetics Animals Biological and medical sciences Classical genetics, quantitative genetics, hybrids Cyclic AMP - analogs & derivatives Cyclic AMP - metabolism Cyclic AMP - pharmacology Cyclic GMP - metabolism Dictyostelium Dictyostelium - cytology Dictyostelium - genetics Dictyostelium - growth & development Fundamental and applied biological sciences. Psychology Gene Deletion Gene Expression Regulation, Fungal - drug effects Genes, Fungal Genetics of eukaryotes. Biological and molecular evolution Kinetics Morphogenesis - drug effects Protozoa RNA, Messenger - analysis RNA, Messenger - biosynthesis Spores, Fungal - physiology Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!