Expression of the Epstein-Barr Virus Immediate Early Gene, BZLF1, in Nasopharyngeal Carcinoma Tumor Cells

The Epstein-Barr virus has been shown to be associated with nasopharyngeal carcinoma (NPC). We have shown that anti-ZEBRA transactivator antibodies were present in sera of most NPC patients. We investigated the expression of the BZLF1 gene in fresh NPC tumor biopsies. RNA transcripts of this gene co...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1993-11, Vol.197 (1), p.358-365
Hauptverfasser:	Cochet, Chantal, Martel-Renoir, Dominique, Grunewald, Virginie, Bosq, Jacques, Cochet, Gilles, Schwaab, Guy, Bernaudin, Jean-François, Joab, Irène
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Biopsy Carcinogenesis, carcinogens and anticarcinogens Consensus Sequence DNA Primers DNA-Binding Proteins - analysis DNA-Binding Proteins - biosynthesis Epstein-Barr virus Exons Gene Expression Genes, Immediate-Early Herpesvirus 4, Human - genetics Humans In Situ Hybridization Introns Medical sciences Molecular Sequence Data Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - microbiology Nasopharyngeal Neoplasms - pathology Polymerase Chain Reaction RNA, Viral - biosynthesis Trans-Activators - analysis Trans-Activators - biosynthesis Transcription, Genetic Tumor Cells, Cultured Tumors Viral Proteins - analysis Viral Proteins - biosynthesis Viruses
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