Co-amplification of the gene for parathyroid hormone-related protein (PTHRP) and KRAS2 in a human lung cancer cell line

Parathyroid hormone‐related protein (PTHRP) is expressed in a large number of tumors and is the mediator of parathyroid hormone‐like effects seen in humoral hypercalcemia of malignancy. The gene coding for PTHRP has been localised to the short arm of chromosome 12. This is at the same region as the...

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Veröffentlicht in:	Genes chromosomes & cancer 1993-08, Vol.7 (4), p.213-218
Hauptverfasser:	Rudduck, Christina, Duncan, Lisa, Center, Rob, Garson, O. Margaret
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Aberrations Chromosome Banding DNA, Neoplasm - analysis Gene Amplification Humans In Situ Hybridization Karyotyping Lung Neoplasms - genetics Neoplasm Proteins - genetics Oncogenes Parathyroid Hormone-Related Protein Proteins - genetics Tumor Cells, Cultured
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