Xanthine oxidase activity in the circulation of rats following hemorrhagic shock

Reactive oxygen metabolites generated from xanthine oxidase play an important role in the pathogenesis of ischemia-induced tissue injury. In a hemorrhagic shock model of ischemia-reperfusion, the intracellular enzyme xanthine oxidase was released into the vasculature. This intravascular source of su...

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Veröffentlicht in:	Free radical biology & medicine 1993-10, Vol.15 (4), p.407-414
Hauptverfasser:	Tan, Sidhartha, Yokoyama, Yoshifumi, Dickens, Eric, Cash, Thomas G., Freeman, Bruce A., Parks, Dale A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Endothelium, Vascular - metabolism Enzymes and enzyme inhibitors Free Radicals Fundamental and applied biological sciences. Psychology Glycosaminoglycans - metabolism Hemorrhage Heparin - blood Hydrogen Peroxide - blood Ischemia L-Lactate Dehydrogenase - blood Liver Male Oxidoreductases Rats Rats, Sprague-Dawley Reperfusion Injury Shock, Hemorrhagic - enzymology Superoxides - blood Xanthine dehydrogenase Xanthine oxidase Xanthine Oxidase - blood
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