Intraduodenal infusion of a water-based levodopa dispersion for optimisation of the therapeutic effect in severe Parkinson's disease

Motor performance of five patients with advanced Parkinson's disease was investigated during their optimum oral therapy (conventional tablets and/or depot capsules) and during a continuous duodenal infusion of levodopa. Due to the low water solubility of the drug, conventional tablets of levodo...

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Veröffentlicht in:	European journal of clinical pharmacology 1993-09, Vol.45 (2), p.117-122
Hauptverfasser:	BREDBERG, E, NILSSON, D, JOHANSSON, K, AQUILONIUS, S.-M, JOHNELS, B, NYSTRÖM, C, PAALZOW, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aged Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Carbidopa - administration & dosage Carbidopa - blood Colloids Female Humans Infusion Pumps Intubation, Gastrointestinal Levodopa - administration & dosage Levodopa - blood Male Medical sciences Middle Aged Motor Skills - physiology Neuropharmacology Parkinson Disease - drug therapy Parkinson Disease - physiopathology Pharmacology. Drug treatments
Online-Zugang:	Volltext
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