Inhibition of canine gastric secretion by the prostanoid Ro 22-6923

The synthetic prostanoid, Ro 22-6923, was studied for its effects on canine gastric secretion. Histamine-stimulated acid secretion was inhibited for up to 8 hr after an orally administered dose of 0.25 mg/kg Ro 22-6923. In the Amdrup (modified Pavlov) pouch model, Ro 22-6923 significantly inhibited...

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Veröffentlicht in:	Digestive diseases and sciences 1985-04, Vol.30 (4), p.340-345
Hauptverfasser:	GAGINELLA, T. S, BERTKO, R. J, MULLER, R. K. M, GALLO-TORRES, H, SULLIVAN, A. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Ulcer Agents - pharmacology Applied sciences Cimetidine - pharmacology Dogs Dose-Response Relationship, Drug Exact sciences and technology Female Gastrectomy Gastric Acid - metabolism Gastric Mucosa - drug effects Gastric Mucosa - metabolism Male Other techniques and industries Prostaglandins E, Synthetic - pharmacology Time Factors
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