Temperature-dependent conformational transitions in poly(dG-dC) and poly(dG-m5dC)

The double‐stranded helical complexes of poly(dG‐dC) and of poly(dG‐m5dC) are shown to convert from B‐ to Z‐DNA‐type conformations at moderate or low ionic strengths, lower for the 5‐methyl than for the non‐methyl species, in a highly cooperative temperature‐dependent equilibrium. In the presence of...

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Veröffentlicht in:	Biopolymers 1985-02, Vol.24 (2), p.289-300
Hauptverfasser:	Behe, Michael J., Felsenfeld, Gary, Szu, Shousun Chen, Charney, Elliot
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cations, Monovalent Conformational dynamics in molecular biology DNA Fundamental and applied biological sciences. Psychology Molecular biophysics Nucleic Acid Conformation Polydeoxyribonucleotides Structure-Activity Relationship Thermodynamics
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