Ethanol administration fails to produce hypoglycemia in fasted chickens ( Gallus domesticus)

1. 1. Chickens weighing approx. 1500g were fasted 64 hr and then continuously infused with [6- 3H]glucose to determine effects of ethanol on plasma glucose concentrations and on rates of glucose turnover. 2. 2. Ethanol infusions (222 or 444μmol/min × kg −1 body weight) did not cause hypoglycemia alt...

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Veröffentlicht in:Comparative biochemistry and physiology. A, Comparative physiology Comparative physiology, 1985, Vol.80 (3), p.419-423
Hauptverfasser: Armstrong, Michael K, Romsos, Dale R
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container_title Comparative biochemistry and physiology. A, Comparative physiology
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Romsos, Dale R
description 1. 1. Chickens weighing approx. 1500g were fasted 64 hr and then continuously infused with [6- 3H]glucose to determine effects of ethanol on plasma glucose concentrations and on rates of glucose turnover. 2. 2. Ethanol infusions (222 or 444μmol/min × kg −1 body weight) did not cause hypoglycemia although the high dose infusion slightly decreased the rate of glucose turnover. 3. 3. Metabolite ratios measured in livers of chickens infused with the high dose of ethanol indicated that the hepatic cytosolic redox state was relatively unchanged. 4. 4. Chickens have an unusual resistance to ethanol-induced hypoglycemia.
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Chickens weighing approx. 1500g were fasted 64 hr and then continuously infused with [6- 3H]glucose to determine effects of ethanol on plasma glucose concentrations and on rates of glucose turnover. 2. 2. Ethanol infusions (222 or 444μmol/min × kg −1 body weight) did not cause hypoglycemia although the high dose infusion slightly decreased the rate of glucose turnover. 3. 3. Metabolite ratios measured in livers of chickens infused with the high dose of ethanol indicated that the hepatic cytosolic redox state was relatively unchanged. 4. 4. 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subjects Alcoholism and acute alcohol poisoning
Animals
Biological and medical sciences
Blood Glucose - metabolism
chickens
Chickens - metabolism
ethanol
Ethanol - pharmacology
Fasting
hypoglycemia
Lactates - blood
Liver - metabolism
Male
Medical sciences
Toxicology
title Ethanol administration fails to produce hypoglycemia in fasted chickens ( Gallus domesticus)
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