Transluminal Stenting in Type A Acute Aortic Dissection: Does the Djumbodis System Have Any Impact on False Lumen Evolution?

Background We reviewed our experience with the transluminal placement of the Djumbodis system in the aortic arch and isthmus in patients with type A acute aortic dissection to assess its impact on true and false aortic lumen evolution. Methods Between January 2005 and September 2009, 50 patients und...

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Veröffentlicht in:The Annals of thoracic surgery 2010-11, Vol.90 (5), p.1450-1456, Article 1450
Hauptverfasser: Ius, Fabio, MD, Vendramin, Igor, MD, Mazzaro, Enzo, MD, Piccoli, Gianluca, MD, Bassi, Flavio, MD, Gasparini, Daniele, MD, Livi, Ugolino, MD
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container_end_page 1456
container_issue 5
container_start_page 1450
container_title The Annals of thoracic surgery
container_volume 90
creator Ius, Fabio, MD
Vendramin, Igor, MD
Mazzaro, Enzo, MD
Piccoli, Gianluca, MD
Bassi, Flavio, MD
Gasparini, Daniele, MD
Livi, Ugolino, MD
description Background We reviewed our experience with the transluminal placement of the Djumbodis system in the aortic arch and isthmus in patients with type A acute aortic dissection to assess its impact on true and false aortic lumen evolution. Methods Between January 2005 and September 2009, 50 patients underwent surgery for type A acute aortic dissection. Twenty-eight patients (group A) were operated on by implanting the Djumbodis prosthesis, and 22 patients (group B) without the prosthesis. Contrast-enhanced computed tomography and magnetic resonance imaging controls were performed on survivors at or soon after discharge and at follow-up. Results Preoperative and operative data and complication rates were not significantly different between the two groups. Three in-hospital deaths occurred within 30 days, 1 in each group due to aortic rupture. At 1- and 4-year follow-up, actuarial survival was 82% ± 7% versus 90% ± 6% and 73% ± 9% versus 84% ± 9%, in group A and B, respectively ( p = 0.35). Three reoperations were performed, 2 in group A and 1 in group B ( p = 0.66). At follow-up, there was no significant difference between groups regarding the ratio between true lumen and aortic diameters and false lumen patency rates at the aortic arch, isthmus, and descending aorta level. Conclusions Placement of the Djumbodis prosthesis does not confer any additional surgical benefit and does not seem to contribute to reducing the incidence of postoperative false lumen patency in patients operated on for type A acute aortic dissection in comparison with conventional surgery.
doi_str_mv 10.1016/j.athoracsur.2010.06.087
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Methods Between January 2005 and September 2009, 50 patients underwent surgery for type A acute aortic dissection. Twenty-eight patients (group A) were operated on by implanting the Djumbodis prosthesis, and 22 patients (group B) without the prosthesis. Contrast-enhanced computed tomography and magnetic resonance imaging controls were performed on survivors at or soon after discharge and at follow-up. Results Preoperative and operative data and complication rates were not significantly different between the two groups. Three in-hospital deaths occurred within 30 days, 1 in each group due to aortic rupture. At 1- and 4-year follow-up, actuarial survival was 82% ± 7% versus 90% ± 6% and 73% ± 9% versus 84% ± 9%, in group A and B, respectively ( p = 0.35). Three reoperations were performed, 2 in group A and 1 in group B ( p = 0.66). At follow-up, there was no significant difference between groups regarding the ratio between true lumen and aortic diameters and false lumen patency rates at the aortic arch, isthmus, and descending aorta level. Conclusions Placement of the Djumbodis prosthesis does not confer any additional surgical benefit and does not seem to contribute to reducing the incidence of postoperative false lumen patency in patients operated on for type A acute aortic dissection in comparison with conventional surgery.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2010.06.087</identifier><identifier>PMID: 20971239</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acute Disease ; Adult ; Aged ; Anesthesia. Intensive care medicine. Transfusions. 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Methods Between January 2005 and September 2009, 50 patients underwent surgery for type A acute aortic dissection. Twenty-eight patients (group A) were operated on by implanting the Djumbodis prosthesis, and 22 patients (group B) without the prosthesis. Contrast-enhanced computed tomography and magnetic resonance imaging controls were performed on survivors at or soon after discharge and at follow-up. Results Preoperative and operative data and complication rates were not significantly different between the two groups. Three in-hospital deaths occurred within 30 days, 1 in each group due to aortic rupture. At 1- and 4-year follow-up, actuarial survival was 82% ± 7% versus 90% ± 6% and 73% ± 9% versus 84% ± 9%, in group A and B, respectively ( p = 0.35). Three reoperations were performed, 2 in group A and 1 in group B ( p = 0.66). At follow-up, there was no significant difference between groups regarding the ratio between true lumen and aortic diameters and false lumen patency rates at the aortic arch, isthmus, and descending aorta level. Conclusions Placement of the Djumbodis prosthesis does not confer any additional surgical benefit and does not seem to contribute to reducing the incidence of postoperative false lumen patency in patients operated on for type A acute aortic dissection in comparison with conventional surgery.</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. 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Diet therapy and various other treatments (general aspects)</topic><topic>Reoperation</topic><topic>Stents</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ius, Fabio, MD</creatorcontrib><creatorcontrib>Vendramin, Igor, MD</creatorcontrib><creatorcontrib>Mazzaro, Enzo, MD</creatorcontrib><creatorcontrib>Piccoli, Gianluca, MD</creatorcontrib><creatorcontrib>Bassi, Flavio, MD</creatorcontrib><creatorcontrib>Gasparini, Daniele, MD</creatorcontrib><creatorcontrib>Livi, Ugolino, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ius, Fabio, MD</au><au>Vendramin, Igor, MD</au><au>Mazzaro, Enzo, MD</au><au>Piccoli, Gianluca, MD</au><au>Bassi, Flavio, MD</au><au>Gasparini, Daniele, MD</au><au>Livi, Ugolino, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transluminal Stenting in Type A Acute Aortic Dissection: Does the Djumbodis System Have Any Impact on False Lumen Evolution?</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2010-11-01</date><risdate>2010</risdate><volume>90</volume><issue>5</issue><spage>1450</spage><epage>1456</epage><pages>1450-1456</pages><artnum>1450</artnum><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background We reviewed our experience with the transluminal placement of the Djumbodis system in the aortic arch and isthmus in patients with type A acute aortic dissection to assess its impact on true and false aortic lumen evolution. 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At follow-up, there was no significant difference between groups regarding the ratio between true lumen and aortic diameters and false lumen patency rates at the aortic arch, isthmus, and descending aorta level. Conclusions Placement of the Djumbodis prosthesis does not confer any additional surgical benefit and does not seem to contribute to reducing the incidence of postoperative false lumen patency in patients operated on for type A acute aortic dissection in comparison with conventional surgery.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>20971239</pmid><doi>10.1016/j.athoracsur.2010.06.087</doi><tpages>7</tpages></addata></record>
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subjects Acute Disease
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Aneurysm, Dissecting - mortality
Aneurysm, Dissecting - surgery
Aorta, Thoracic - pathology
Aortic Aneurysm - mortality
Aortic Aneurysm - surgery
Biological and medical sciences
Blood Vessel Prosthesis Implantation - adverse effects
Blood Vessel Prosthesis Implantation - methods
Cardiology. Vascular system
Cardiothoracic Surgery
Diseases of the cardiovascular system
Female
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Pneumology
Postoperative Complications - etiology
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Reoperation
Stents
Surgery
title Transluminal Stenting in Type A Acute Aortic Dissection: Does the Djumbodis System Have Any Impact on False Lumen Evolution?
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