Hydrocarbon Nephropathy in Male Rats: Identification of the Nephrotoxic Components of Unleaded Gasoline

Previous subchronic and/or chronic inhalation studies of unleaded gasoline and a variety of petroleum naphthas, solvents, and distillates have shown that these complex materials are capable of inducing a distinctive nephropathy which appears limited to male rats. Therefore a series of gavage screeni...

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Veröffentlicht in:	Toxicology and industrial health 1985-11, Vol.1 (3), p.67-87
Hauptverfasser:	Halder, Clive A., Holdsworth, Charles E., Cockrell, Beverly Y., Piccirillo, Vincent J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkanes - toxicity Animals Body Weight - drug effects Gasoline - analysis Gasoline - toxicity Hydrocarbons - toxicity Kidney - pathology Kidney Diseases - chemically induced Male Organ Size - drug effects Petroleum - toxicity Rats Rats, Inbred F344 Structure-Activity Relationship
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