Sequence-regulated vinyl copolymers by metal-catalysed step-growth radical polymerization
Proteins and nucleic acids are sequence-regulated macromolecules with various properties originating from their perfectly sequenced primary structures. However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polym...
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| Veröffentlicht in: | Nature communications 2010-04, Vol.1 (1), p.1-6, Article 6 |
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| creator | Kamigaito, Masami Satoh, Kotaro Ozawa, Satoshi Mizutani, Masato Nagai, Kanji |
| description | Proteins and nucleic acids are sequence-regulated macromolecules with various properties originating from their perfectly sequenced primary structures. However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polymer chemistry. In this study, we report a strategy to obtain sequence-regulated vinyl copolymers consisting of styrene, acrylate and vinyl chloride units using metal-catalysed step-growth radical polyaddition of designed monomers prepared from common vinyl monomer building blocks. Unprecedented ABCC-sequence-regulated copolymers with perfect vinyl chloride–styrene–acrylate–acrylate sequences were obtained by copper-catalysed step-growth radical polymerization of designed monomers possessing unconjugated C=C and reactive C–Cl bonds. This strategy may open a new route in the study of sequence-regulated synthetic polymers.
The synthesis of sequence-regulated copolymers continues to challenge polymer chemists. Here step-growth radical polymerisation of designed abc and abcc monomers leads to vinyl copolymers with repeating ABC and ABCC sequences. |
| doi_str_mv | 10.1038/ncomms1004 |
| format | Article |
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The synthesis of sequence-regulated copolymers continues to challenge polymer chemists. Here step-growth radical polymerisation of designed abc and abcc monomers leads to vinyl copolymers with repeating ABC and ABCC sequences.</description><identifier>ISSN: 2041-1723</identifier><identifier>EISSN: 2041-1723</identifier><identifier>DOI: 10.1038/ncomms1004</identifier><identifier>PMID: 20975670</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>639/301/923/1028 ; 639/638/455 ; Catalysis ; Humanities and Social Sciences ; Magnetic Resonance Spectroscopy ; Metals - chemistry ; Molecular Structure ; multidisciplinary ; Polymerization ; Polymers - chemistry ; Polyvinyl Chloride - chemistry ; Science ; Science (multidisciplinary) ; Styrene - chemistry ; Vinyl Compounds - chemistry</subject><ispartof>Nature communications, 2010-04, Vol.1 (1), p.1-6, Article 6</ispartof><rights>Springer Nature Limited 2010</rights><rights>Copyright Nature Publishing Group Apr 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c487t-fa9f86e02ea54261952632c159331cbb64d303f9f6e64f5c7f717c4748e7deae3</citedby><cites>FETCH-LOGICAL-c487t-fa9f86e02ea54261952632c159331cbb64d303f9f6e64f5c7f717c4748e7deae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27933,27934</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20975670$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamigaito, Masami</creatorcontrib><creatorcontrib>Satoh, Kotaro</creatorcontrib><creatorcontrib>Ozawa, Satoshi</creatorcontrib><creatorcontrib>Mizutani, Masato</creatorcontrib><creatorcontrib>Nagai, Kanji</creatorcontrib><title>Sequence-regulated vinyl copolymers by metal-catalysed step-growth radical polymerization</title><title>Nature communications</title><addtitle>Nat Commun</addtitle><addtitle>Nat Commun</addtitle><description>Proteins and nucleic acids are sequence-regulated macromolecules with various properties originating from their perfectly sequenced primary structures. However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polymer chemistry. In this study, we report a strategy to obtain sequence-regulated vinyl copolymers consisting of styrene, acrylate and vinyl chloride units using metal-catalysed step-growth radical polyaddition of designed monomers prepared from common vinyl monomer building blocks. Unprecedented ABCC-sequence-regulated copolymers with perfect vinyl chloride–styrene–acrylate–acrylate sequences were obtained by copper-catalysed step-growth radical polymerization of designed monomers possessing unconjugated C=C and reactive C–Cl bonds. This strategy may open a new route in the study of sequence-regulated synthetic polymers.
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However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polymer chemistry. In this study, we report a strategy to obtain sequence-regulated vinyl copolymers consisting of styrene, acrylate and vinyl chloride units using metal-catalysed step-growth radical polyaddition of designed monomers prepared from common vinyl monomer building blocks. Unprecedented ABCC-sequence-regulated copolymers with perfect vinyl chloride–styrene–acrylate–acrylate sequences were obtained by copper-catalysed step-growth radical polymerization of designed monomers possessing unconjugated C=C and reactive C–Cl bonds. This strategy may open a new route in the study of sequence-regulated synthetic polymers.
The synthesis of sequence-regulated copolymers continues to challenge polymer chemists. Here step-growth radical polymerisation of designed abc and abcc monomers leads to vinyl copolymers with repeating ABC and ABCC sequences.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>20975670</pmid><doi>10.1038/ncomms1004</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 639/301/923/1028 639/638/455 Catalysis Humanities and Social Sciences Magnetic Resonance Spectroscopy Metals - chemistry Molecular Structure multidisciplinary Polymerization Polymers - chemistry Polyvinyl Chloride - chemistry Science Science (multidisciplinary) Styrene - chemistry Vinyl Compounds - chemistry |
| title | Sequence-regulated vinyl copolymers by metal-catalysed step-growth radical polymerization |
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