Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations

It has been almost a decade since a previously unknown human toxic syndrome, azaspiracid poisoning (AZP), emerged as the cause of severe gastrointestinal illness in humans after the consumption of mussels ( Mytilus edulis). Structural studies indicated that these toxins, azaspiracids, were of a new...

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Veröffentlicht in:	Toxicon (Oxford) 2010-08, Vol.56 (2), p.173-190
Hauptverfasser:	Furey, Ambrose, O'Doherty, Sinead, O'Callaghan, Keith, Lehane, Mary, James, Kevin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Azaspiracids AZP Cell Line, Tumor Cell Survival - drug effects Chromatography, High Pressure Liquid Foodborne Diseases Human Humans Intestine, Small - drug effects Intestine, Small - ultrastructure LC-MS Lung Neoplasms - chemically induced Lung Neoplasms - pathology Marine Marine toxins Marine Toxins - chemistry Marine Toxins - poisoning Metabolites Methylation Mice Microscopy, Electron, Scanning Molecular Structure Mussels Mytilus edulis Mytilus edulis - chemistry Mytilus edulis - metabolism Neurons - drug effects Neurons - pathology Poisoning Shellfish Shellfish Poisoning - etiology Shellfish Poisoning - metabolism Spectrometry, Mass, Electrospray Ionization Spiro Compounds - chemistry Spiro Compounds - poisoning Tandem Mass Spectrometry Toxicity Tests Toxins Tumours
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